CAS 135295-27-1

9-(3-fluoro-2-phosphonylmethoxypropyl)adenine

Description:

9-(3-Fluoro-2-phosphonylmethoxypropyl)adenine, with the CAS number 135295-27-1, is a synthetic nucleoside analog that exhibits structural similarities to adenine, a fundamental component of nucleic acids. This compound features a fluorinated side chain and a phosphonylmethoxy group, which contribute to its potential biological activity. The presence of the phosphonyl group enhances its stability and bioavailability, making it a candidate for antiviral and anticancer research. Its fluorine substitution may influence the compound's interaction with biological targets, potentially altering its pharmacokinetic properties. As a nucleoside analog, it may interfere with nucleic acid synthesis, thereby inhibiting the replication of viruses or cancer cells. The compound's characteristics, including solubility, stability, and reactivity, are crucial for its application in medicinal chemistry and drug development. Further studies are necessary to fully elucidate its mechanism of action and therapeutic potential.

Formula: C₉H₁₃FN₅O₄P

InChI: InChI=1/C9H13FN5O4P/c10-1-6(19-5-20(16,17)18)2-15-4-14-7-8(11)12-3-13-9(7)15/h3-4,6H,1-2,5H2,(H2,11,12,13)(H2,16,17,18)

SMILES: C(C(Cn1cnc2c(N)ncnc12)OCP(=O)(O)O)F

Synonyms:

• 3-Fpmpa
• Phosphonic acid, ((2-(6-amino-9H-purin-9-yl)-1-(fluoromethyl)ethoxy)methyl)-, (+-)-
• ({[1-(6-amino-9H-purin-9-yl)-3-fluoropropan-2-yl]oxy}methyl)phosphonic acid

(2RS)-FPMPA

CAS: 135295-27-1

(2RS)-FPMPA

Purity: ≥98%

Molecular weight: 305.2g/mol

Ref: 54-BUP02790

(2RS)-FPMPA

CAS: 135295-27-1

(2RS)-FPMPA（FPMPA） has antiviral activity with an IC50 value of 1.85 μM measured in human MT12 cells infected with SHIV (DH4R).

Formula: C₉H₁₃FN₅O₄P

Purity: 99.9% - >99.99%

Color and Shape: Solid

Molecular weight: 305.2

Ref: TM-T67798