CAS 13535-01-8

3-Amino-5-bromopyridine

Description:

3-Amino-5-bromopyridine is an organic compound characterized by the presence of an amino group (-NH2) and a bromine atom attached to a pyridine ring, which is a six-membered aromatic heterocycle containing one nitrogen atom. This compound typically appears as a solid and is soluble in polar solvents due to the amino group, which can engage in hydrogen bonding. The bromine substituent introduces both electronic and steric effects, influencing the compound's reactivity and potential applications in organic synthesis. 3-Amino-5-bromopyridine is often utilized as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. Its reactivity can be attributed to the nucleophilic nature of the amino group and the electrophilic character of the bromine, allowing for various substitution reactions. Additionally, the compound's structure may exhibit tautomerism and can participate in various chemical transformations, making it a valuable building block in medicinal chemistry and materials science. Safety data should be consulted for handling and storage, as with all chemical substances.

Formula: C₅H₅ClN₂

InChI: InChI=1/C5H5ClN2/c6-4-1-5(7)3-8-2-4/h1-3H,7H2

SMILES: c1c(cncc1N)Cl

Synonyms:

• 3-Pyridinamine, 5-bromo-
• 5-Brom-3-pyridinamin
• 5-Bromopyridin-3-amine
• 5-Brompyridin-3-amin
• 5-Chloropyridin-3-Amine
• 5-Bromo-3-pyridinamine

5-Bromopyridin-3-amine

CAS: 13535-01-8

Formula: C₅H₅BrN₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 173.0106

Ref: IN-DA003MI4

3-Amino-5-bromopyridine

CAS: 13535-01-8

Purity: 98%

Molecular weight: 173.011

Ref: FT-A12982

3-Amino-5-bromopyridine

CAS: 13535-01-8

3-Amino-5-bromopyridine

Formula: C₅H₅BrN₂

Purity: 98%

Color and Shape: light orange solid

Molecular weight: 173.01g/mol

Ref: 54-OR9578

3-Amino-5-bromopyridine

CAS: 13535-01-8

Formula: C₅H₅BrN₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 173.013

Ref: 10-F033123

3-Amino-5-bromopyridine

CAS: 13535-01-8

3-Amino-5-bromopyridine (3ABP) is a linker for the synthesis of cisplatin. It has been shown to have strong bactericidal activity against Escherichia coli and Staphylococcus aureus. 3ABP is cytotoxic to both renal proximal tubule cells and ring-opening cells, which are found in the kidney. It is also an inhibitor of nicotinic acetylcholine receptors (nAChRs), which are proteins that control nerve cell communication. 3ABP's pharmacokinetic properties make it suitable as a linker for cisplatin, as it has good oral bioavailability, low systemic toxicity, and high tissue selectivity.

Formula: C₅H₅BrN₂

Purity: Min. 98 Area-%

Molecular weight: 173.01 g/mol

Ref: 3D-FA45810