CAS 135415-73-5

FL118

CAS: 135415-73-5

FL118

Purity: ≥98%

Molecular weight: 392.36g/mol

Ref: 54-BUP01646

FL118

CAS: 135415-73-5

FL118 is a novel survivin inhibitor that inhibits cancer stem cell-like properties.FL118 is a novel camptothecin analog with anticancer activity that inhibits

Formula: C₂₁H₁₆N₂O₆

Purity: 97.14%

Color and Shape: Soild

Molecular weight: 392.36

Ref: TM-T77701

10,11-Methylenedioxycamptothecin

CAS: 135415-73-5

10,11-Methylenedioxycamptothecin (10,11-MDCT) is a nitro drug and an analog of camptothecin. It has significant cytotoxic activity against tumor cell lines and inhibits protein synthesis in these cells. 10,11-MDCT has been shown to have a binding constant with DNA of approximately 1 nM and binds to the minor groove of the DNA helix. It also has been shown to inhibit the transport of drugs across membranes that contain phospholipids. Studies on 10,11-MDCT in prostate cancer cells show that it is more potent than doxorubicin in inhibiting cell growth and inducing apoptosis. 10,11-MDCT also inhibits glycoside derivatives that are involved in the synthesis of DNA, RNA and proteins.

Formula: C₂₁H₁₆N₂O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 392.4 g/mol

Ref: 3D-FM179869