CAS 135416-43-2

CAINDEXNAME:8-AZABICYCLO[3.2.1]OCTANE-2-CARBOXYLIC

Description:

8-Azabicyclo[3.2.1]octane-2-carboxylic acid, identified by the CAS number 135416-43-2, is a bicyclic compound featuring a nitrogen atom within its ring structure, which classifies it as a bicyclic amine. This compound exhibits a carboxylic acid functional group, contributing to its acidic properties. The bicyclic framework consists of two fused rings, providing unique steric and electronic characteristics that can influence its reactivity and interaction with biological systems. The presence of the nitrogen atom in the bicyclic structure may also impart basicity, allowing it to participate in various chemical reactions, including nucleophilic substitutions. This compound is of interest in medicinal chemistry, particularly for its potential applications in drug development, as its structural features may enhance binding affinity to biological targets. Additionally, its solubility and stability in different solvents can vary, affecting its utility in various chemical processes. Overall, 8-azabicyclo[3.2.1]octane-2-carboxylic acid represents a versatile scaffold for further chemical modifications and investigations.

Formula: C₁₆H₂₀INO₂

InChI: InChI=1S/C16H20INO2/c1-18-12-7-8-14(18)15(16(19)20-2)13(9-12)10-3-5-11(17)6-4-10/h3-6,12-15H,7-9H2,1-2H3/t12-,13+,14+,15-/m0/s1

InChI key: InChIKey=SIIICDNNMDMWCI-YJNKXOJESA-N

SMILES: C(OC)(=O)[C@H]1[C@H](C[C@]2(N(C)[C@@]1(CC2)[H])[H])C3=CC=C(I)C=C3

Synonyms:

• (()-2-beta-Carbomethoxy-3-beta-(4-iodophenyl)tropane
• 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(4-iodophenyl)-8-methyl, methyl ester, (1R,2S,3S,5S)-
• 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(4-iodophenyl)-8-methyl-, methyl ester, [1R-(exo,exo)]-
• Iometopane
• Methyl (1R,2S,3S,5S)-3-(4-iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
• Rti 4229-98
• Rti 55
• β-CIT

(1R,2S,3S,5S)-3-(4-Iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylicacid methyl ester

Controlled Product

CAS: 135416-43-2

(1R,2S,3S,5S)-3-(4-Iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylicacid methyl ester is a molecule that has been shown to be effective in lowering the symptoms of Parkinson's disease. It also prevents the uptake of dopamine and serotonin in the brain by binding to dopamine and serotonin transporters on the cell membrane. This drug has been shown to be safe at doses up to 100 mg/kg/day in rats, but has not been tested in humans. The drug is stable in neutral pH environments and does not degrade upon exposure to light or oxygen.

Formula: C₁₆H₂₀INO₂

Purity: Min. 95%

Molecular weight: 385.24 g/mol

Ref: 3D-FI76761

RTI-55

CAS: 135416-43-2

RTI-55 is an inhibitor of non-selective dopamine reuptake.

Formula: C₁₆H₂₀INO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 385.24

Ref: TM-T28621