CAS 1354396-23-8

Ceftazidime Ep Impurity H

Description:

Ceftazidime Ep Impurity H, with the CAS number 1354396-23-8, is a chemical compound associated with the antibiotic ceftazidime, which belongs to the class of cephalosporins. This impurity is typically a byproduct formed during the synthesis or degradation of ceftazidime. It may exhibit characteristics such as a specific molecular structure that includes a beta-lactam ring, which is essential for its antibacterial activity. The presence of impurities like Ceftazidime Ep Impurity H can affect the purity and efficacy of the final pharmaceutical product. In terms of solubility, it is likely to be soluble in polar solvents, consistent with many cephalosporin derivatives. The identification and quantification of such impurities are crucial in pharmaceutical development to ensure safety, efficacy, and compliance with regulatory standards. Analytical techniques such as high-performance liquid chromatography (HPLC) are commonly employed to detect and measure these impurities in drug formulations. Understanding the characteristics of such impurities helps in optimizing the manufacturing process and ensuring the quality of the final product.

Formula: C₂₃H₂₄N₆O₇S₂

Synonyms:

• Ceftazidime Methyl Ester (Contain ~10% triethylammonium iodide)
• Ceftazidime Impurity H (EP) (Ceftazidime Methyl Ester )
• Ceftazidime Methyl Ester (Contains ~10% triethylammonium iodide)
• Methyl Ester Ceftazidi H (EP)
• Ceftazidime Ep Impurity H
• (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(1-methoxy-2-methyl-1-oxopropan-2-yl)oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• Ceftazidime impurity 7/Ceftazidime EP Impurity H/Ceftazidime Methyl Ester/(6R,7R)-7-[[(2Z)-2-(2-aminothiazol-4-yl)-2-[(2-methoxy-1,1-dimethyl-2-oxoethoxy)imino]acetyl]amino]-8-oxo-3-[(1-pyridinio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• Ceftazidime Methyl Ester (>85%)
• Ceftazidime Impurity 8(Ceftazidime EP Impurity H)

Ceftazidime EP Impurity H

CAS: 1354396-23-8

Formula: C₂₃H₂₄N₆O₇S₂

Molecular weight: 560.60

Ref: 4Z-C-10506

Ceftazidime Methyl Ester (>85%)

Controlled Product

CAS: 1354396-23-8

Impurity Ceftazidime EP Impurity H
Applications Ceftazidime Methyl Ester (Ceftazidime EP Impurity H) is an impurity of Ceftazidime (C244100). Ceftazidime impurity G.
References Miyake, A., et al.: Antimicrob. Agents Chemother., 486, 182 (1989), Seibert, G., et al.: Arzneim.-Forsch., 33, 1084 (1983),

Formula: C₂₃H₂₄N₆O₇S₂

Purity: >85%

Color and Shape: Neat

Molecular weight: 560.60

Ref: TR-C244120

Ceftazidime impurity H

CAS: 1354396-23-8

Ceftazidime impurity H is a by-product that can be found in the synthesis of ceftazidime. It has been detected using magnetic separation and UV detection. Ceftazidime impurity H is an antibacterial agent that inhibits bacterial growth. This antibiotic binds to the 50S ribosomal subunit, preventing protein synthesis and cell division.

Formula: C₂₃H₂₄N₆O₇S₂

Purity: Min. 95%

Molecular weight: 560.6 g/mol

Ref: 3D-IC63721

Ceftazidime EP Impurity H

CAS: 1354396-23-8

Formula: C₂₃H₂₄N₆O₇S₂

Molecular weight: 560.6

Ref: ST-EA-CP-C12008