PDE10A-IN-8, with the CAS number 1354404-30-0, is a selective inhibitor of the enzyme phosphodiesterase 10A (PDE10A), which plays a crucial role in the regulation of intracellular signaling pathways by hydrolyzing cyclic nucleotides such as cAMP and cGMP. This compound is primarily studied for its potential therapeutic applications in neurological disorders, particularly in the treatment of schizophrenia and other cognitive impairments. PDE10A-IN-8 exhibits high selectivity for PDE10A over other phosphodiesterases, which is essential for minimizing side effects associated with broader inhibition. The compound's pharmacological profile suggests that it may enhance dopaminergic and glutamatergic signaling, potentially improving cognitive function. In terms of its chemical structure, PDE10A-IN-8 features specific functional groups that contribute to its binding affinity and selectivity for the target enzyme. Ongoing research continues to explore its efficacy and safety in clinical settings, making it a compound of interest in medicinal chemistry and drug development.

PDE10A-IN-8 is a potent PDE10A inhibitor.

PDE10A-IN-8

1354404-30-0: PDE10A-IN-8, with the CAS number 1354404-30-0, is a selective inhibitor of the enzyme phosphodiesterase 10A (PDE10A), which plays a crucial role in the regulation of intracellular signaling pathways by hydrolyzing cyclic nucleotides such as cAMP and cGMP. This compound is primarily studied for its potential therapeutic applications in neurological disorders, particularly in the treatment of schizophrenia and other cognitive impairments. PDE10A-IN-8 exhibits high selectivity for PDE10A over other phosphodiesterases, which is essential for minimizing side effects associated with broader inhibition. The compound's pharmacological profile suggests that it may enhance dopaminergic and glutamatergic signaling, potentially improving cognitive function. In terms of its chemical structure, PDE10A-IN-8 features specific functional groups that contribute to its binding affinity and selectivity for the target enzyme. Ongoing research continues to explore its efficacy and safety in clinical settings, making it a compound of interest in medicinal chemistry and drug development.

<p>PDE10A-IN-8 is a potent inhibitor of PDE10A.</p>

CAS 1354404-30-0

PDE10A-IN-8

PDE10A-IN-8

Ref: TM-T28350