CAS 1354631-24-5

[1-​(5-​fluoropentyl)​-​1H-​indol-​3-​yl]​(4-​methyl-​1-​naphthalenyl)​methanone

Description:

The chemical substance known as [1-(5-fluoropentyl)-1H-indol-3-yl](4-methyl-1-naphthalenyl)methanone, with the CAS number 1354631-24-5, is a synthetic compound that belongs to the class of indole derivatives. It features a complex structure characterized by an indole moiety substituted with a fluoropentyl group and a naphthalenyl group linked through a ketone functional group. This compound is often studied for its potential pharmacological properties, particularly in relation to cannabinoid receptor activity, as it may exhibit effects similar to those of cannabinoids. Its unique structure allows for interactions with biological systems, which can lead to various physiological effects. The presence of the fluorine atom may enhance lipophilicity and influence the compound's binding affinity to receptors. As with many synthetic cannabinoids, the safety profile, toxicity, and legal status can vary significantly, necessitating careful consideration in research and application contexts. Overall, this compound represents a notable example of the ongoing exploration of synthetic analogs in medicinal chemistry.

Formula: C₂₅H₂₄FNO

InChI: InChI=1S/C25H24FNO/c1-18-13-14-22(20-10-4-3-9-19(18)20)25(28)23-17-27(16-8-2-7-15-26)24-12-6-5-11-21(23)24/h3-6,9-14,17H,2,7-8,15-16H2,1H3

InChI key: InChIKey=IGBHZHCGWLHBAE-UHFFFAOYSA-N

SMILES: C(=O)(C=1C=2C(N(CCCCCF)C1)=CC=CC2)C=3C4=C(C(C)=CC3)C=CC=C4

Synonyms:

• AM 2201-pMe
• Mam 2201
• Methanone, [1-(5-fluoropentyl)-1H-indol-3-yl](4-methyl-1-naphthalenyl)-
• 4-Methyl AM-2201
• 1-(5-fluoropentyl)-3-(4-Methyl-1-naphthoyl)indole
• [1-(5-Fluoropentyl)-1H-indol-3-yl](4-Methyl-1-naphthalenyl)Methanone
• [1-(5-fluoropentyl)indol-3-yl]-(4-methylnaphthalen-1-yl)methanone
• MAM-2201, JWH-122 N-(5-Fluoropentyl) analogue
• 5MAM-2201
• (1-(5-fluoropentyl)-1H-indol-3-yl)(4-Methylnaphthalen-1-yl)Methanone

MAM-2201, 0.1mg/ml in Methanol

Controlled Product

CAS: 1354631-24-5

Color and Shape: Single Solution

Ref: LP-MAM-1739-0.1LM

MAM-2201

Controlled Product

CAS: 1354631-24-5

Color and Shape: Neat

Ref: LP-MAM-1739-10

4-Methyl AM-2201 (1 mg/ml in Acetonitrile)

Controlled Product

CAS: 1354631-24-5

Formula: C₂₅H₂₄FNO

Color and Shape: Single Solution

Molecular weight: 373.46

Ref: TR-KIT5765

4-Methyl AM-2201

Controlled Product

CAS: 1354631-24-5

Applications 4-Methyl AM-2201 is an analogue of AM-2201 (A575830).Synthetic Cannabinoids

Formula: C₂₅H₂₄FNO

Color and Shape: Neat

Molecular weight: 373.46

Ref: TR-M265110

MAM2201 N-(2-Fluoropentyl) Isomer

Controlled Product

CAS: 1354631-24-5

Formula: C₂₅H₂₄FNO

Color and Shape: Neat

Molecular weight: 373.50

Ref: TR-M161555

MAM 2201

Controlled Product

CAS: 1354631-24-5

MAM 2201 is a novel, potent, selective CB2 receptor agonist with high affinity for the CB2 receptor. The compound has a favorable pharmacokinetic profile and displays low acute toxicity in vivo. It is also highly selective for the CB2 receptor and does not interact with other receptors or ion channels in vitro. MAM 2201 is metabolized by CYP3A4 to an active metabolite that binds to the CB2 receptor with high affinity. The drug also inhibits energy metabolism in cells, which may be responsible for its anti-inflammatory effect.

Formula: C₂₅H₂₄FNO

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 373.46 g/mol

Ref: 3D-FF32986