CAS 13551-89-8

Fluoromisonidazole

Description:

Fluoromisonidazole (CAS 13551-89-8) is a chemical compound primarily recognized for its application in the field of radiopharmaceuticals and as a hypoxia marker in cancer research. It is a nitroimidazole derivative, which means it contains a nitro group (-NO2) attached to an imidazole ring. This structure allows it to selectively accumulate in hypoxic (low oxygen) tissues, making it useful for imaging and therapeutic purposes in oncology. Fluoromisonidazole is characterized by its relatively low solubility in water, which can influence its bioavailability and distribution in biological systems. The compound is often utilized in positron emission tomography (PET) imaging to assess tumor hypoxia, providing valuable insights into tumor behavior and treatment response. Additionally, its chemical stability and ability to form reactive metabolites contribute to its effectiveness in targeting hypoxic cells. Overall, Fluoromisonidazole serves as a significant tool in both diagnostic and therapeutic applications in cancer research.

Formula: C₆H₈FN₃O₃

InChI: InChI=1S/C6H8FN3O3/c7-3-5(11)4-9-2-1-8-6(9)10(12)13/h1-2,5,11H,3-4H2

InChI key: InChIKey=HIIJZYSUEJYLMX-UHFFFAOYSA-N

SMILES: N(=O)(=O)C=1N(CC(CF)O)C=CN1

Synonyms:

• 1-(2-Nitro-1-Imidazolyl)-3-Fluoro-2-Propanol
• 1-fluoro-3-(2-nitro-1 H-imidazol-1-yl)propan-2-ol
• 1-fluoro-3-(2-nitro-1H-imidazol-1-yl)propan-2-ol
• 1H-Imidazole-1-Ethanol, Beta-(Fluoromethyl)-2-Nitro-
• 1H-Imidazole-1-Ethanol,Alpha-(Fluoromethyl)-2-Nitro
• 1H-Imidazole-1-ethanol, α-(fluoromethyl)-2-nitro-
• Alpha-(Fluoromethyl)-2-Nitro-Imidazole-1-Ethano
• Alpha-(Fluoromethyl)-2-Nitroimidazole-1-Ethanol
• Fluoromisonidazole
• Fmiso
• Imidazole-1-ethanol, α-(fluoromethyl)-2-nitro-
• Ku 2210
• NSC 292930
• Ro 07-0741
• Sr 1367

Fluoromisonidazole

CAS: 13551-89-8

Formula: C₆H₈FN₃O₃

Color and Shape: Neat

Molecular weight: 189.144

Ref: TR-F445900

Fluoromisonidazole

CAS: 13551-89-8

Fluoromisonidazole, a Radiation-Sensitizing Agent, can be used for imaging tumor hypoxia: imaging the microenvironment for personalized cancer therapy.

Formula: C₆H₈FN₃O₃

Color and Shape: Yellow Solid

Molecular weight: 189.14

Ref: TM-T31825