CAS 13551-90-1
:2-nitro-1-(oxiran-2-ylmethyl)-1H-imidazole
Description:
2-Nitro-1-(oxiran-2-ylmethyl)-1H-imidazole is a chemical compound characterized by its imidazole ring, which is a five-membered heterocyclic structure containing two nitrogen atoms. The presence of a nitro group (-NO2) at the 2-position of the imidazole ring contributes to its reactivity and potential applications in various chemical reactions. The oxirane (epoxide) moiety at the 1-position introduces a three-membered cyclic ether, which is known for its strain and reactivity, particularly in nucleophilic ring-opening reactions. This compound may exhibit biological activity, making it of interest in medicinal chemistry and pharmacology. Its unique structure allows for potential interactions with biological targets, and it may serve as a building block in the synthesis of more complex molecules. Additionally, the compound's properties, such as solubility, stability, and reactivity, can be influenced by the functional groups present, making it a subject of study in organic synthesis and material science.
Formula:C6H7N3O3
InChI:InChI=1/C6H7N3O3/c10-9(11)6-7-1-2-8(6)3-5-4-12-5/h1-2,5H,3-4H2
SMILES:c1cn(CC2CO2)c(n1)N(=O)=O
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Found 3 products.
1-(2,3-Epoxypropyl)-2-nitroimidazole
CAS:Controlled Product<p>Applications 1-(2,3-Epoxypropyl)-2-nitroimidazole is an intermediate in the synthesis of Pimonidazole-d10 (P447814). Isotope labelled Pimonidazole (P447813) is an effective and nontoxic hypoxia detection reagent. Pimonidazole forms adducts with thiol groups in proteins, peptides and amino acids. It abels hypoxic tumor cells in vivo. Also labels hypoxic mesenchymal stem cells in mouse bone marrow.<br>References Sato et al.: PLoS One 11 e0165946 PMID:(2016); Bennewith et al.: Cancer Res. 62 6827 PMID: 12460894, (2002)<br></p>Formula:C6H7N3O3Color and Shape:NeatMolecular weight:169.14
