Boc-Pen(Trt)-OH, also known as Boc-protected penicillamine, is a chemical compound characterized by its protective groups that enhance its stability and solubility in various solvents. The "Boc" (tert-butyloxycarbonyl) group serves as a protecting group for the amino functionality, while "Trt" (trityl) protects the thiol group, making it useful in peptide synthesis and other organic reactions. This compound is typically used in the field of medicinal chemistry and peptide synthesis due to its ability to facilitate the selective modification of amino acids. It is generally a white to off-white solid and is soluble in organic solvents like dichloromethane and dimethylformamide. The presence of the penicillamine structure contributes to its potential biological activity, particularly in chelation therapy and as a precursor in the synthesis of various pharmaceuticals. As with many chemical substances, proper handling and storage are essential to maintain its integrity and prevent degradation.

Boc-Pen(Trt)-OH

135592-13-1: Boc-Pen(Trt)-OH, also known as Boc-protected penicillamine, is a chemical compound characterized by its protective groups that enhance its stability and solubility in various solvents. The "Boc" (tert-butyloxycarbonyl) group serves as a protecting group for the amino functionality, while "Trt" (trityl) protects the thiol group, making it useful in peptide synthesis and other organic reactions. This compound is typically used in the field of medicinal chemistry and peptide synthesis due to its ability to facilitate the selective modification of amino acids. It is generally a white to off-white solid and is soluble in organic solvents like dichloromethane and dimethylformamide. The presence of the penicillamine structure contributes to its potential biological activity, particularly in chelation therapy and as a precursor in the synthesis of various pharmaceuticals. As with many chemical substances, proper handling and storage are essential to maintain its integrity and prevent degradation.

Coupling of peptide thioesters to N-terminal penicillamine (introduced as Boc-Pen(Trt)) followed by desulfuration yielding valine broadens the scope of Native Chemical Ligation.

BOC-PEN(TRT)-OH

(R)-2-((tert-Butoxycarbonyl)amino)-3-methyl-3-(tritylthio)butanoic acid

CAS 135592-13-1

Boc-Pen(Trt)-OH

Boc-Pen(Trt)-OH

Ref: 01-4019781

BOC-PEN(TRT)-OH

Ref: IN-DA006YHO

(R)-2-((tert-Butoxycarbonyl)amino)-3-methyl-3-(tritylthio)butanoic acid

Ref: 54-OR1061870

(R)-2-((tert-butoxycarbonyl)amino)-3-methyl-3-(tritylthio)butanoic acid

Ref: 10-F768969