CAS 135610-90-1

Fmoc-D-His(1-Trt)-OH

Description:

Fmoc-D-His(1-Trt)-OH, with the CAS number 135610-90-1, is a protected amino acid derivative commonly used in peptide synthesis. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino function, allowing for selective reactions during peptide assembly. The "D-His" indicates that the amino acid is a D-enantiomer of histidine, which is important in specific biological contexts. The "1-Trt" refers to the trityl (Trt) protection on the side chain of histidine, which protects the imidazole group, preventing unwanted reactions during synthesis. This compound is typically utilized in solid-phase peptide synthesis due to its stability and compatibility with various coupling reagents. Its structure allows for the introduction of histidine residues into peptides, which can be crucial for biological activity, metal ion binding, or as a site for further modifications. Overall, Fmoc-D-His(1-Trt)-OH is a valuable building block in the field of peptide chemistry and biochemistry.

Formula: C₄₀H₃₃N₃O₄

InChI: InChI=1/C40H33N3O4/c44-38(45)37(42-39(46)47-26-36-34-22-12-10-20-32(34)33-21-11-13-23-35(33)36)24-31-25-43(27-41-31)40(28-14-4-1-5-15-28,29-16-6-2-7-17-29)30-18-8-3-9-19-30/h1-23,25,27,36-37H,24,26H2,(H,42,46)(H,44,45)/t37-/m1/s1

SMILES: c1ccc(cc1)C(c1ccccc1)(c1ccccc1)n1cc(C[C@H](C(=O)O)N=C(O)OCC2c3ccccc3c3ccccc23)nc1

Synonyms:

• Fmoc-D-His(Trt)-OH
• (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-tritylimidazol-4-yl)propanoic acid
• N-Fmoc-N'-trityl-D-histidine
• FMOC-N-IM-TRITYL-D-HISTIDINE
• FMOC-D-HISTIDINE(1-TRT)-OH
• FMOC-D-HIS(1-TRT)-OH
• N-ALPHA-FMOC-N-IM-TRITYL-D-HISTIDINE
• FMOC-D-HIS(TRT)
• FMOC-D-HISTIDINE(TRITYL)
• N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-IM-TRITYL-D-HISTIDINE
• N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-TAU-TRITYL D-HISTIDINE
• FMOC-D-HIS(T-TRT)-OH
• NALPHA-9-Fluorenylmethoxycarbonyl-Nim-trityl-D-histidine
• N-α-Fmoc-N-im-trityl-D-histidine

N-Fmoc-1-trityl-D-histidine, 98%

CAS: 135610-90-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₄₀H₃₃N₃O₄

Purity: 98%

Molecular weight: 619.72

Ref: 02-H62504

Fmoc-D-His(1-Trt)-OH

CAS: 135610-90-1

Bachem ID: 4014118.

Formula: C₄₀H₃₃N₃O₄

Purity: 99.9%

Color and Shape: White

Molecular weight: 619.72

Ref: 01-4014118

D-Histidine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-1-(triphenylmethyl)-

CAS: 135610-90-1

Formula: C₄₀H₃₃N₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 619.7077

Ref: IN-DA00HU9D

N-α-Fmoc-N-IM-Trityl-D-Histidine

CAS: 135610-90-1

N-α-Fmoc-N-IM-Trityl-D-Histidine

Purity: 98%

Molecular weight: 619.71g/mol

Ref: 54-OR1014247

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-τ-(triphenylmethyl)-D-histidine

CAS: 135610-90-1

Formula: C₄₀H₃₃N₃O₄

Purity: >97.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 619.72

Ref: 3B-F1145

Fmoc-D-His(Trt)-OH

CAS: 135610-90-1

Fmoc-D-His(Trt)-OH is a chiral building block that is used in peptide synthesis. It can be used to synthesize an enantiomer or homologue of the original amino acid. Fmoc-D-His(Trt)-OH has been postulated to exist as two stereoisomers, 1R,2S and 2R,1S. The 1R,2S enantiomer is the naturally occurring form of this compound and is produced with a shift of +6 ppm in the proton NMR spectrum. The 2R,1S enantiomer has also been observed in the solid state but not in solution and it exhibits a shift of -6 ppm in the proton NMR spectrum.
Fmoc-D-His(Trt)-OH is soluble in solvents such as DMSO and DMF. It has also been shown to be a potent inhibitor of organophosphate and re

Formula: C₄₀H₃₃N₃O₄

Purity: Min. 95%

Molecular weight: 619.73 g/mol

Ref: 3D-FDH-1812-PI

Fmoc-D-His(Trt)-OH

CAS: 135610-90-1

M03417 - Fmoc-D-His(Trt)-OH

Formula: C₄₀H₃₃N₃O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 619.721

Ref: 10-M03417