CAS 135654-16-9
:3-(CHLOROMETHYL)BENZAMIDE
Description:
3-(Chloromethyl)benzamide is an organic compound characterized by the presence of a benzamide functional group with a chloromethyl substituent at the meta position. Its molecular structure consists of a benzene ring attached to a carbonyl group (amide) and a chloromethyl group (-CH2Cl). This compound typically appears as a white to off-white solid and is soluble in organic solvents. It is important in organic synthesis and can serve as an intermediate in the production of pharmaceuticals and agrochemicals. The presence of the chloromethyl group makes it a potential electrophile, allowing it to participate in various chemical reactions, such as nucleophilic substitutions. Safety data indicates that it should be handled with care, as it may pose health risks upon exposure. Proper storage in a cool, dry place away from incompatible substances is recommended to maintain its stability. As with many chemical substances, it is essential to consult safety data sheets and follow appropriate laboratory protocols when working with 3-(chloromethyl)benzamide.
Formula:C8H8ClNO
InChI:InChI=1/C8H8ClNO/c9-5-6-2-1-3-7(4-6)8(10)11/h1-4H,5H2,(H2,10,11)
SMILES:c1cc(cc(c1)C(=N)O)CCl
Synonyms:- Benzamide, 3-(chloromethyl)- (9CI)
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Found 4 products.
3-(Chloromethyl)benzamide
CAS:Formula:C8H8ClNOPurity:97%Color and Shape:SolidMolecular weight:169.60823-(Chloromethyl)benzamide
CAS:3-(Chloromethyl)benzamidePurity:95%Color and Shape:White SolidMolecular weight:169.61g/mol3-Chloromethylbenzamide
CAS:<p>3-Chloromethylbenzamide is a potent inhibitor of cyclic nucleotide phosphodiesterases. It is synthesised from dimethylformamide and propenoic acid, and has been shown to be effective in the treatment of cancer. 3-Chloromethylbenzamide inhibits the activity of cyclic nucleotide phosphodiesterases, which are enzymes that break down cyclic AMP and cAMP. This inhibition leads to an increase in intracellular levels of these nucleotides, which can result in cancer cell death by apoptosis. 3-Chloromethylbenzamide has also been shown to be a potent inhibitor of hydroxymethylglutaryl coenzyme A reductase (HMGCR), which is the enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid. The inhibition of this enzyme leads to decreased production of cholesterol and other steroids, as well as increased levels of meval</p>Formula:C8H8ClNOPurity:Min. 95%Molecular weight:169.61 g/mol



