Trandolaprilat-phenyl-D5 is a deuterated derivative of trandolaprilat, which is an active metabolite of the angiotensin-converting enzyme (ACE) inhibitor trandolapril. This compound is characterized by its incorporation of deuterium, a stable isotope of hydrogen, which can enhance its pharmacokinetic properties and facilitate studies in metabolic pathways. Trandolaprilat itself is known for its ability to lower blood pressure by inhibiting the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. The presence of the phenyl-D5 moiety suggests that the compound may be used in research to trace metabolic processes or to study the pharmacodynamics and pharmacokinetics of trandolaprilat in biological systems. The deuterated form can also help in reducing the rate of metabolism, potentially leading to prolonged action in therapeutic applications. Overall, trandolaprilat-phenyl-D5 serves as a valuable tool in both clinical and research settings, particularly in the study of cardiovascular pharmacology.

TRANDOLAPRILAT-PHENYL-D5

1356841-27-4: Trandolaprilat-phenyl-D5 is a deuterated derivative of trandolaprilat, which is an active metabolite of the angiotensin-converting enzyme (ACE) inhibitor trandolapril. This compound is characterized by its incorporation of deuterium, a stable isotope of hydrogen, which can enhance its pharmacokinetic properties and facilitate studies in metabolic pathways. Trandolaprilat itself is known for its ability to lower blood pressure by inhibiting the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. The presence of the phenyl-D5 moiety suggests that the compound may be used in research to trace metabolic processes or to study the pharmacodynamics and pharmacokinetics of trandolaprilat in biological systems. The deuterated form can also help in reducing the rate of metabolism, potentially leading to prolonged action in therapeutic applications. Overall, trandolaprilat-phenyl-D5 serves as a valuable tool in both clinical and research settings, particularly in the study of cardiovascular pharmacology.

Trandolaprilate D5 is a deuterium-labeled Trandolaprilate. Trandolaprilate is an inhibitor of angiotensin-converting enzyme (ACE).

Trandolaprilate D5

<p>Applications A Labelled metabolite of Trandolapril, an antihypertensive.<br>References Blankley, C.J., et al.: J. Med. Chem., 30, 992 (1987)<br></p>

CAS 1356841-27-4

TRANDOLAPRILAT-PHENYL-D5

Trandolaprilate D5

Ref: TM-T13196

Trandolaprilat-phenyl-d5

Ref: TR-T713522