Amylin fragment 8-37, also known as human amylin or islet amyloid polypeptide (IAPP) fragment, is a peptide that consists of 30 amino acids, specifically derived from the human amylin molecule. The CAS number 135702-23-7 identifies this specific fragment, which is a truncated form of the full-length amylin peptide. This fragment is notable for its role in glucose metabolism and its involvement in the pathophysiology of type 2 diabetes, where it can aggregate and form amyloid deposits in pancreatic islets. The peptide is characterized by its hydrophobic nature, which contributes to its propensity to misfold and aggregate. Additionally, amylin fragment 8-37 has been studied for its potential neuroprotective effects and its ability to modulate appetite and energy expenditure. Its biological activity is influenced by its structure, which includes specific amino acid sequences that interact with receptors in the body, making it a subject of interest in diabetes research and therapeutic development.

amylin fragment 8-37 human

135702-23-7: Amylin fragment 8-37, also known as human amylin or islet amyloid polypeptide (IAPP) fragment, is a peptide that consists of 30 amino acids, specifically derived from the human amylin molecule. The CAS number 135702-23-7 identifies this specific fragment, which is a truncated form of the full-length amylin peptide. This fragment is notable for its role in glucose metabolism and its involvement in the pathophysiology of type 2 diabetes, where it can aggregate and form amyloid deposits in pancreatic islets. The peptide is characterized by its hydrophobic nature, which contributes to its propensity to misfold and aggregate. Additionally, amylin fragment 8-37 has been studied for its potential neuroprotective effects and its ability to modulate appetite and energy expenditure. Its biological activity is influenced by its structure, which includes specific amino acid sequences that interact with receptors in the body, making it a subject of interest in diabetes research and therapeutic development.

Human IAPP (8-37), ATQRLANFLVHSSNNFGAILSSTNVGSNTY-amide, readily forms fibrils in vitro.

Amylin (8-37) (human)

<p>Human-derived Amylin (8-37) is a vasodilator in rat arteries and forms aggregates linked to type II diabetes.</p>

Amylin (8-37), human

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CAS 135702-23-7

amylin fragment 8-37 human

Amylin (8-37) (human)

Ref: 01-4030202

Amylin (8-37), human

Ref: TM-T38764

Amylin (8-37) (human) trifluoroacetate salt

Ref: 3D-FA108762