CAS 135729-62-3: Palonosetron Hydrochloride

Description:Palonosetron hydrochloride is a selective serotonin 5-HT3 receptor antagonist primarily used as an antiemetic to prevent nausea and vomiting associated with chemotherapy and surgery. It is characterized by its high affinity for the 5-HT3 receptor, which allows it to effectively block the action of serotonin, a neurotransmitter involved in the vomiting reflex. The substance is typically administered intravenously or orally, and it has a longer half-life compared to other 5-HT3 antagonists, allowing for less frequent dosing. Palonosetron hydrochloride is known for its efficacy in both acute and delayed nausea and vomiting, making it a valuable option in clinical settings. Its chemical structure includes a bicyclic core, contributing to its pharmacological properties. Additionally, it is generally well-tolerated, with a side effect profile that may include headache, constipation, and dizziness. As with any medication, it is important to consider contraindications and potential interactions with other drugs when prescribing palonosetron hydrochloride.

Formula:C₁₉H₂₄N₂O·ClH

InChI:InChI=1S/C19H24N2O.ClH/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-21(19)17-12-20-9-7-13(17)8-10-20;/h2,4,6,13,15,17H,1,3,5,7-12H2;1H/t15-,17-;/m1./s1

InChI key:InChIKey=OLDRWYVIKMSFFB-SSPJITILSA-N

SMILES:Cl.O=C1C2=CC=CC3=C2C(CN1C4CN5CCC4CC5)CCC3

Synonyms:
(3aR)-2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one hydrochloride (1:1)
(3aS)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one Hydrochloride
(3aS)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one monohydrochloride
(3aS)-2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one hydrochloride
(S,S)-Palonosetron Hydrochloride
1H-Benz[de]isoquinolin-1-one, 2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-, monohydrochloride, [S-(R*,R*)]-
1H-Benz[de]isoquinolin-1-one, 2-(3S)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-, monohydrochloride, (3aS)-
1H-Benz[de]isoquinolin-1-one, 2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-, hydrochloride (1:1), (3aS)-
Aloxi
Onicit
See more synonyms
Palonosetron HCl(RR)
Palonosetron HCl(RS)
Palonosetron HCl(SR)
Palonosetron Hcl
ROSUVASTATIN CALCIUM/calcium,7-[4-(4-fluorophenyl)-2-(methyl-methylsulfonyl-amino)-6-propan-2-yl-pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoate
Rs 25259-197
Palonosetron hydrochloride
Palonosetron. Hydrochloride

Found 13 products.

Product data	Purity	Price range	Estimated delivery
Palonosetron Hydrochloride REF: 3B-P2051CAS: 135729-61-2 135729-62-3	>98.0%(T)(HPLC)	84.00 €~291.00 €	Mon 17 Mar 25
Palonosetron Hydrochloride REF: 45-1492200CAS: 135729-62-3	- - -	463.00 €	Tue 25 Mar 25
Palonosetron hydrochloride REF: TM-T1156CAS: 135729-62-3	99.84% - 99.92%	51.00 €~133.00 €	Mon 24 Mar 25
1H-Benz[de]isoquinolin-1-one, 2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-, hydrochloride (1:1), (3aS)- REF: IN-DA00360JCAS: 135729-62-3	98%	58.00 €~578.00 €	Mon 24 Mar 25
Palonosetron-d3 HCl REF: 4Z-P-532CAS: 135729-62-3	- - -	To inquire	Tue 25 Mar 25
Palonosetron HCl REF: 4Z-P-531CAS: 135729-62-3	- - -	To inquire	Tue 25 Mar 25
Palonosetron hydrochloride REF: 7W-GP2375CAS: 135729-62-3	≥ 98.0%	152.00 €~398.00 €	Tue 25 Mar 25
Palonosetron Hydrochloride REF: 86-MM3779.00-0250CAS: 135729-62-3	- - -	268.00 €	Thu 27 Mar 25
Palonosetron hydrochloride REF: AC-46299CAS: 135729-62-3	- - -	To inquire	Thu 27 Mar 25
(S,S)-Palonosetron Hydrochloride REF: TR-P165800CAS: 135729-62-3	- - -	135.00 €~1,255.00 €	Thu 03 Apr 25
Palonosetron hydrochloride REF: 10-F463448CAS: 135729-62-3	95.0%	To inquire	Thu 03 Apr 25
Palonosetron HCl - Bio-X ™ REF: 3D-BP164227CAS: 135729-62-3	Min. 95%	145.00 €	Fri 04 Apr 25
Palonosetron hydrochloride REF: 3D-FP14811CAS: 135729-62-3	Min. 95%	222.00 €~1,799.00 €	Fri 04 Apr 25