CAS 1357389-11-7
:RGFP966
Description:
RGFP966, with the CAS number 1357389-11-7, is a small molecule inhibitor primarily known for its role in modulating the activity of histone deacetylases (HDACs), particularly HDAC1 and HDAC2. This compound has garnered attention in the field of cancer research due to its potential to induce differentiation and apoptosis in various cancer cell lines. RGFP966 is characterized by its ability to cross the blood-brain barrier, making it a candidate for neurological applications as well. Its mechanism of action involves the alteration of gene expression through the inhibition of histone deacetylation, leading to an increase in acetylated histones and a subsequent change in chromatin structure. This can result in the reactivation of tumor suppressor genes and the downregulation of oncogenes. Additionally, RGFP966 has been studied for its neuroprotective effects, suggesting potential therapeutic applications in neurodegenerative diseases. However, further research is necessary to fully elucidate its pharmacological profile and therapeutic potential.
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Found 7 products.
(E)-N-(2-Amino-4-fluorophenyl)-3-(1-cinnamyl-1H-pyrazol-4-yl)acrylamide
CAS:(E)-N-(2-Amino-4-fluorophenyl)-3-(1-cinnamyl-1H-pyrazol-4-yl)acrylamidePurity:98%Molecular weight:362.4g/molRGFP966
CAS:<p>RGFP966 is an HDAC3 inhibitor (IC50: 0.08 μM) and does not affect other HDACs at concentrations up to 15 μM.</p>Formula:C21H19FN4OPurity:99.2% - 99.88%Color and Shape:SolidMolecular weight:362.4RGFP 966
CAS:<p>Inhibitor of class 1 histone deacetylase (HDAC)</p>Formula:C21H19FN4OPurity:Min. 95%Molecular weight:362.4 g/mol
