
CAS 135755-51-0
:1H-Benz[de]isoquinolin-1-one,2-(3S)-1- azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6- hexahydro-,monohydrochloride,(3aR)-
Description:
1H-Benz[de]isoquinolin-1-one, 2-(3S)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-, monohydrochloride, (3aR)-, is a complex organic compound characterized by its unique bicyclic structure, which incorporates both isoquinoline and azabicyclo components. This substance typically exhibits properties associated with both aromatic and aliphatic systems, contributing to its potential biological activity. The presence of the hydrochloride indicates that it is a salt form, which often enhances solubility in aqueous solutions, making it suitable for various pharmaceutical applications. The stereochemistry, particularly the (3S) and (3aR) configurations, suggests specific spatial arrangements that can influence the compound's interaction with biological targets, potentially affecting its pharmacodynamics and pharmacokinetics. Such compounds are often investigated for their therapeutic potential, particularly in the fields of neuroscience and medicinal chemistry, due to their ability to interact with neurotransmitter systems. Overall, this compound represents a fascinating area of study within the realm of organic and medicinal chemistry.
- (R,S)-Palonosetron Hydrochloride
- (3aR)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one Hydrochloride
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Found 5 products.
Palonosetron Related Compound D ((R)-2-[(3S)-Quinuclidin-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one hydrochloride)
CAS:Lactams, nesoiFormula:C19H24N2O·HClColor and Shape:White Yellow PowderMolecular weight:332.87 g/mol(R)-2-((1R,3S,4R)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one hydrochloride
CAS:Formula:C19H25ClN2OPurity:99%Color and Shape:SolidMolecular weight:332.8676Palonosetron USP Related Compound D ((R,S)-Palonosetron HCl)
CAS:Formula:C19H24N2O·HClColor and Shape:White To Off-White SolidMolecular weight:296.41 36.46(R,S)-Palonosetron Hydrochloride (90%)
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications The (R,S)-enantiomer of Palonosetron (P165800), a potent and selective antagonist, with 5-HT3 receptor in vitro. An impurity of Palonosetron.<br>References Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),<br></p>Formula:C19H24N2O·ClHPurity:90%Color and Shape:NeatMolecular weight:332.87





