CAS 1358-76-5

Koumine

Description:

Koumine is a chemical compound classified as an alkaloid, primarily derived from the plant species *Gelsemium elegans*. It is known for its structural complexity, featuring a bicyclic framework that contributes to its biological activity. Koumine exhibits a range of pharmacological properties, including analgesic and anti-inflammatory effects, which have garnered interest in medicinal chemistry. The compound interacts with various biological targets, potentially influencing neurotransmitter systems. Its CAS number, 1358-76-5, is a unique identifier that facilitates the cataloging and study of this substance in scientific literature. In terms of solubility, koumine is typically soluble in organic solvents, which is common for many alkaloids. However, its stability and reactivity can vary depending on environmental conditions such as pH and temperature. Research into koumine continues, focusing on its potential therapeutic applications and mechanisms of action, as well as its safety profile and toxicity in biological systems.

Formula: C₂₀H₂₂N₂O

InChI: InChI=1/C20H22N2O/c1-3-19-11-22(2)16-9-20(19)13-6-4-5-7-15(13)21-18(20)17-8-14(19)12(16)10-23-17/h3-7,12,14,16-17H,1,8-11H2,2H3/t12?,14-,16?,17-,19+,20?/m1/s1

InChI key: InChIKey=VTLYEMHGPMGUOT-XCNGAKDKSA-N

SMILES: C(=C)[C@@]12[C@]34C([C@]5(C[C@@]1([C@@]([C@](C3)(N(C)C2)[H])(CO5)[H])[H])[H])=NC=6C4=CC=CC6

Synonyms:

• (3S,4S,4aR,6R,11bS,11cS)-11c-Ethenyl-1,2,3,4,4a,5,6,11c-octahydro-2-methyl-6,4-(epoxymethano)-3,11b-methano-11bH-pyrido[4,3-c]carbazole
• (4aR,6R,11cS)-11c-ethenyl-2-methyl-1,2,3,4,4a,5,6,11c-octahydro-6,4-(epoxymethano)-3,11b-methanopyrido[4,3-c]carbazole
• 6,4-(Epoxymethano)-3,11b-methano-11bH-pyrido[4,3-c]carbazole, 11c-ethenyl-1,2,3,4,4a,5,6,11c-octahydro-2-methyl-, (3S,4S,4aR,6R,11bS,11cS)-
• 6,4-(Epoxymethano)-3,11b-methano-11bH-pyrido[4,3-c]carbazole, 7,20(2H,19H)-cyclovobasan deriv.
• 6,4-(epoxymethano)-3,11b-methano-11bH-pyrido[4,3-c]carbazole, 11c-ethenyl-1,2,3,4,4a,5,6,11c-octahydro-2-methyl-, (4aR,6R,11cS)-
• 7,20(2H,19H)-Cyclovobasan, 1,2,18,19-tetradehydro-3,17-epoxy-, (3R,7α,20α)-
• 7,20(2H,19H)-Cyclovobasan, 1,2,18,19-tetradehydro-3,17-epoxy-,(3R,7alpha,20alpha)-
• Koumine
• (3R,7alpha,20alpha)-1,2,18,19-Tetradehydro-3,17-epoxy-7,20(2H,19H)cyclovobasan

Koumine

CAS: 1358-76-5

Formula: C₂₀H₂₂N₂O

Purity: 95%

Color and Shape: Solid

Molecular weight: 306.4015

Ref: IN-DA009GNS

Koumine

CAS: 1358-76-5

Formula: C₂₀H₂₂N₂O

Molecular weight: 306.41

Ref: 7W-GY1546

Koumine

CAS: 1358-76-5

Koumine

Purity: ≥98%

Molecular weight: 306.4g/mol

Ref: 54-BUP00120

Koumine

CAS: 1358-76-5

Formula: C₂₀H₂₂N₂O

Purity: 95%~99%

Molecular weight: 306.409

Ref: BP-BP0832

Koumine

CAS: 1358-76-5

Koumine may treat diabetic neuropathy, has antineoplastic properties for breast cancer, and relieves pain by increasing spinal allopregnanolone.

Formula: C₂₀H₂₂N₂O

Purity: 98.83% - 99.69%

Color and Shape: Solid

Molecular weight: 306.40

Ref: TM-T5S0661

Koumine

CAS: 1358-76-5

Natural alkaloid

Formula: C₂₀H₂₂N₂O

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 306.4

Ref: 5G-84231

Koumine

Controlled Product

CAS: 1358-76-5

Koumine is an alkaloid compound, which is a naturally occurring chemical derived from the Gelsemium genus of plants. It functions primarily by interacting with various neurotransmitter receptors, exhibiting modulating effects that influence neural pathways. This mode of action underlies its potential therapeutic significance.

Formula: C₂₀H₂₂N₂O

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 306.40 g/mol

Ref: 3D-FK73903