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CAS 1358201-44-1

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  • P162-0948
    Targetmol
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    P162-0948

    CAS:
    <p>P162-0948 is a selective CDK8 inhibitor with an IC50 value of 50.4 nM. It reduces cell migration and the expression of EMT-related proteins in the A549 human alveolar epithelial cell line. Furthermore, P162-0948 decreases Smad phosphorylation, indicating disruption of the TGF-β/Smad signaling pathway, making it a promising compound for pulmonary fibrosis research.</p>
    Formula:C20H15FN4O2
    Color and Shape:Solid
    Molecular weight:362.357

    Ref: TM-T205592