Big endothelin-1 (often referred to as big endothelin) is a precursor form of the endothelin peptides, which are potent vasoconstrictors involved in various physiological processes, including blood pressure regulation and cardiovascular function. The specific substance "big endothelin 39 rat" corresponds to a variant derived from rat sources, with the CAS number 135842-15-8 indicating its unique chemical identity. This peptide is characterized by its relatively large molecular structure, consisting of a sequence of amino acids that undergo enzymatic cleavage to produce active endothelin-1, endothelin-2, or endothelin-3. Big endothelin plays a crucial role in the endothelin system, influencing vascular tone and cellular proliferation. It is also implicated in various pathophysiological conditions, such as hypertension and heart failure. Research on big endothelin and its derivatives continues to provide insights into their roles in health and disease, making them important targets for therapeutic interventions in cardiovascular disorders.

big endothelin 39 rat

135842-15-8: Big endothelin-1 (often referred to as big endothelin) is a precursor form of the endothelin peptides, which are potent vasoconstrictors involved in various physiological processes, including blood pressure regulation and cardiovascular function. The specific substance "big endothelin 39 rat" corresponds to a variant derived from rat sources, with the CAS number 135842-15-8 indicating its unique chemical identity. This peptide is characterized by its relatively large molecular structure, consisting of a sequence of amino acids that undergo enzymatic cleavage to produce active endothelin-1, endothelin-2, or endothelin-3. Big endothelin plays a crucial role in the endothelin system, influencing vascular tone and cellular proliferation. It is also implicated in various pathophysiological conditions, such as hypertension and heart failure. Research on big endothelin and its derivatives continues to provide insights into their roles in health and disease, making them important targets for therapeutic interventions in cardiovascular disorders.

Big endothelin-1 (rat 1-39), a 39-residue peptide, induces a diuretic and natriuretic response in conscious Sprague-Dawley rats and elevates blood pressure in

CAS 135842-15-8

big endothelin 39 rat

Big endothelin-1 (rat 1-39)

Ref: TM-T82886