CAS 1358581-37-9

(2S,3R,4S,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-tetrahydro-6-(hydroxymethyl)-2-methoxy-2H-pyran-3,4,5-triol

Description:

The chemical substance with the name "(2S,3R,4S,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-tetrahydro-6-(hydroxymethyl)-2-methoxy-2H-pyran-3,4,5-triol" and CAS number "1358581-37-9" is a complex organic compound characterized by its specific stereochemistry and functional groups. It features a tetrahydropyran ring, which is a six-membered cyclic ether, and multiple hydroxymethyl and methoxy substituents that contribute to its reactivity and solubility. The presence of a thiophene ring, particularly with a fluorophenyl substitution, suggests potential applications in medicinal chemistry, possibly as a pharmaceutical agent. The stereochemical configuration indicated by the (2S,3R,4S,5S,6R) notation implies that the compound has multiple chiral centers, which can significantly influence its biological activity and interaction with biological targets. Overall, this compound's intricate structure and functional groups make it a subject of interest for further research in various chemical and biological applications.

2-Methoxy Canagliflozin

Controlled Product

CAS: 1358581-37-9

Applications 1-Methoxy Canagliflozin is an impurity in the synthesis of the drug Canagliflozin (C175190). Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.
References Chao, E. et al.: Drug Fut., 36, 351 (2011); Sha, S. et al.: Diab. Obes. Metab., 13, 669 (2011); Kipnes, M.S.: Clin. Invest., 1, 145 (2011);

Formula: C₂₅H₂₇FO₆S

Color and Shape: Neat

Molecular weight: 474.542

Ref: TR-M261385

Canagliflozin Impurity 1

CAS: 1358581-37-9

Formula: C₂₅H₂₇FO₆S

Molecular weight: 474.54

Ref: ST-EA-CP-C7009