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CAS 1358617-36-3

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    BC-1901S

    CAS:
    BC-1901S functions as a proteasome-independent activator and stabilizer of NRF2. By binding to DCAF1 (E3 ligase subunit), it disrupts the NRF2/DCAF1 interaction and activates NRF2 through the inhibition of NRF2 ubiquitination, independent of KEAP1. BC-1901S has demonstrated anti-inflammatory effects in a murine model of LPS-induced acute lung injury.
    Formula:C23H22ClFN4O
    Molecular weight:424.90

    Ref: TM-T87995