CAS 13589-07-6

L-Valyl-L-histidine

Description:

L-Valyl-L-histidine is a dipeptide composed of the amino acids valine and histidine, linked by a peptide bond. It is characterized by its specific sequence, where valine (L-Val) is the N-terminal amino acid and histidine (L-His) is the C-terminal amino acid. This compound is typically found in biological systems and can play roles in various physiological processes. L-Valyl-L-histidine is known for its potential to influence protein synthesis and may exhibit bioactive properties, making it of interest in nutritional and pharmaceutical research. The presence of the imidazole side chain from histidine contributes to its ability to participate in enzyme catalysis and metal ion coordination. Additionally, the hydrophobic nature of valine can affect the peptide's solubility and interaction with other biomolecules. As a dipeptide, it may also be involved in signaling pathways and can serve as a building block for larger peptides and proteins. Its stability and reactivity can be influenced by environmental factors such as pH and temperature.

Formula: C₁₁H₁₈N₄O₃

InChI: InChI=1S/C11H18N4O3/c1-6(2)9(12)10(16)15-8(11(17)18)3-7-4-13-5-14-7/h4-6,8-9H,3,12H2,1-2H3,(H,13,14)(H,15,16)(H,17,18)/t8-,9-/m0/s1

InChI key: InChIKey=BNQVUHQWZGTIBX-IUCAKERBSA-N

SMILES: [C@@H](CC1=CN=CN1)(NC([C@H](C(C)C)N)=O)C(O)=O

Synonyms:

• Histidine, N-L-valyl-, L-
• L-Valyl-L-histidine
• L-Histidine, N-L-valyl-
• Valylhistidine
• L-Histidine, L-valyl-

H-Val-His-OH

CAS: 13589-07-6

Corresponds to the N-terminus of the β-chain of hemoglobin A which reacts with blood glucose yielding hemoglobin A1c.

Formula: C₁₁H₁₈N₄O₃

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 254.29

Ref: 01-4002910

H-Val-His-OH

CAS: 13589-07-6

H-Val-His-OH is a skin condition that can be treated by an efficient method. The method has been validated and has shown to be effective in the treatment of cryptococcus neoformans, which is a yeast that causes infection in humans. Amino acid analysis of H-Val-His-OH has shown it to be an amination reaction product of histidine and valine. The ph profile was found to be constant at 3.5 and the sample was pretreated with acid before being analyzed using chromatographic methods. This compound may have potential use as a fungicide or antibiotic because it has been found to inhibit oxidases, which are enzymes that break down organic compounds. These results were obtained through testing with erythrocytes from calf thymus DNA and bacterial DNA gyrase, dna topoisomerase, and rna synthesis.

Formula: C₁₁H₁₈N₄O₃

Purity: Min. 95%

Molecular weight: 254.29 g/mol

Ref: 3D-FV108226

L-Valyl-L-histidine

CAS: 13589-07-6

Formula: C₁₁H₁₈N₄O₃

Molecular weight: 254.29

Ref: ST-EA-CP-H30015