CAS 135910-20-2

dalvastatin

Description:

Dalvastatin, with the CAS number 135910-20-2, is a synthetic compound that belongs to the class of statins, which are primarily used for their cholesterol-lowering properties. It functions by inhibiting the enzyme HMG-CoA reductase, a key player in the biosynthesis of cholesterol in the liver. This action leads to a decrease in low-density lipoprotein (LDL) cholesterol levels and an increase in high-density lipoprotein (HDL) cholesterol levels, contributing to cardiovascular health. Dalvastatin is characterized by its specific molecular structure, which includes a lactone ring and various functional groups that enhance its pharmacological activity. The compound is typically administered orally and is subject to extensive metabolism in the liver. Its efficacy and safety profile are evaluated through clinical studies, which assess its impact on lipid profiles and potential side effects. As with other statins, common side effects may include muscle pain, liver enzyme alterations, and gastrointestinal disturbances. Overall, dalvastatin represents a valuable therapeutic option in the management of dyslipidemia and cardiovascular risk.

Formula: C₂₄H₃₁FO₃

InChI: InChI=1/C24H31FO3/c1-15-10-16(6-9-21(15)25)19-13-23(2,3)14-24(4,5)20(19)8-7-18-11-17(26)12-22(27)28-18/h6-10,17-18,26H,11-14H2,1-5H3/b8-7+/t17-,18-/m1/s1

Synonyms:

• (4R,6S)-rel-6-((1E)-2-(2-(4-Fluoro-3-methylphenyl)-4,4,6,6-tetramethyl-1-cyclohexen-1-yl)ethenyl)tetrahydro-4-hydroxy-2H-pyran-2-one
• 2H-Pyran-2-one, 6-((1E)-2-(2-(4-fluoro-3-methylphenyl)-4,4,6,6-tetramethyl-1-cyclohexen-1-yl)ethenyl)tetrahydro-4-hydroxy-, (4R,6S)-rel-
• (4R,6S)-6-{(E)-2-[2-(4-fluoro-3-methylphenyl)-4,4,6,6-tetramethylcyclohex-1-en-1-yl]ethenyl}-4-hydroxytetrahydro-2H-pyran-2-one