CAS 135944-05-7

FMOC-ALPHA-METHYL-L-PHE

Description:

FMOC-alpha-methyl-L-phenylalanine (FMOC-α-Me-L-Phe) is a derivative of the amino acid phenylalanine, characterized by the presence of a 9-fluorenylmethoxycarbonyl (FMOC) protective group. This compound is commonly used in peptide synthesis as a building block due to its ability to protect the amino group during the coupling reactions. The alpha-methyl group enhances the steric hindrance, which can influence the conformation and reactivity of the resulting peptides. FMOC-α-Me-L-Phe is typically a white to off-white solid and is soluble in organic solvents like dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. Its stability under standard laboratory conditions makes it a valuable reagent in organic synthesis and biochemistry. Additionally, the FMOC group can be easily removed under mild basic conditions, allowing for the subsequent formation of peptide bonds. Overall, FMOC-α-Me-L-Phe is an important compound in the field of peptide chemistry, facilitating the synthesis of various biologically active peptides.

Formula: C₂₅H₂₃NO₄

InChI: InChI=1/C25H23NO4/c1-25(23(27)28,15-17-9-3-2-4-10-17)26-24(29)30-16-22-20-13-7-5-11-18(20)19-12-6-8-14-21(19)22/h2-14,22H,15-16H2,1H3,(H,26,29)(H,27,28)/t25-/m0/s1

SMILES: C[C@](Cc1ccccc1)(C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12

Synonyms:

• Fmoc-(S)-2-Amino-2-Methyl-3-Phenylpropanoic Acid
• Fmoc-Alpha-Benzyl-L-Ala
• Fmoc-Alpha-Me-Phe-Oh
• Fmoc-Alpha-Methyl-L-Phenylalanine
• Fmoc-Alpha-Methyl-Phenylalanine
• Fmoc-á-Me-Phe-OH
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-alpha-methyl-L-phenylalanine

Fmoc-α-Me-Phe-OH

CAS: 135944-05-7

Bachem ID: 4084334.

Formula: C₂₅H₂₃NO₄

Purity: 99.9%

Color and Shape: White

Molecular weight: 401.46

Ref: 01-4084334

Fmoc-α-Methyl-L-Phe

CAS: 135944-05-7

Formula: C₂₅H₂₃NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 401.4544

Ref: IN-DA009B18

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methyl-3-phenylpropanoic acid

CAS: 135944-05-7

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methyl-3-phenylpropanoic acid

Purity: 98%

Molecular weight: 401.45g/mol

Ref: 54-OR76139

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methyl-3-phenylpropanoic acid

CAS: 135944-05-7

Purity: 97%

Molecular weight: 401.4620056

Ref: 10-F616767

Fmoc-a-methyl-L-phenylalanine

Controlled Product

CAS: 135944-05-7

Applications Fmoc-alpha-methyl-L-phenylalanine

Formula: C₂₅H₂₃NO₄

Color and Shape: Neat

Molecular weight: 401.45

Ref: TR-F603535

Fmoc-α-methyl-L-phenylalanine

CAS: 135944-05-7

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Formula: C₂₅H₂₃NO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 401.45 g/mol

Ref: 3D-FF49805