CAS 135970-30-8

Benzyl D-Glucuronate

Description:

Benzyl D-glucuronate is a chemical compound characterized by its glucuronate moiety, which is a derivative of D-glucuronic acid. It features a benzyl group attached to the glucuronate structure, enhancing its solubility and reactivity. This compound is typically used in biochemical research and pharmaceutical applications, particularly in drug metabolism studies, as glucuronidation is a key phase II metabolic pathway for detoxifying various substances. Benzyl D-glucuronate can participate in conjugation reactions, where it may serve as a substrate for enzymes such as UDP-glucuronosyltransferases. Its properties include being a white to off-white solid, soluble in water and organic solvents, and it may exhibit specific optical activity due to its chiral nature. The compound's stability and reactivity can be influenced by pH and temperature, making it important to handle under controlled conditions. Overall, Benzyl D-glucuronate serves as a valuable tool in understanding metabolic processes and the pharmacokinetics of drugs.

Formula: C₁₃H₁₆O₇

InChI: InChI=1/C13H16O7/c14-8-9(15)11(20-12(17)10(8)16)13(18)19-6-7-4-2-1-3-5-7/h1-5,8-12,14-17H,6H2/t8?,9-,10-,11?,12?/m0/s1

SMILES: c1ccc(cc1)COC(=O)C1[C@H](C([C@@H](C(O)O1)O)O)O

Synonyms:

• D-Glucuronic Acid Phenylmethyl Ester
• Glucuronic Acid Benzyl Ester

Benzyl D-glucuronate

CAS: 135970-30-8

Ref: 7W-GC9536

Benzyl D-Glucuronate

Controlled Product

CAS: 135970-30-8

Stability Hygroscopic
Applications Used in efficient synthesis of 1β-O-acyl glucuronides via regioselective acylation
References Meng, X., et al.: J. Med. Chem., 50, 6165 (2007),

Formula: C₁₃H₁₆O₇

Color and Shape: Neat

Molecular weight: 284.26

Ref: TR-B279800

Benzyl D-glucuronate

CAS: 135970-30-8

Used for the synthesis of 1β-O-acyl glucuronides

Formula: C₁₃H₁₆O₇

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 284.26 g/mol

Ref: 3D-MB07246