CAS 13599-12-7

ethyl 3-phenyl-1H-pyrazole-5-carboxylate

Description:

Ethyl 3-phenyl-1H-pyrazole-5-carboxylate, with the CAS number 13599-12-7, is an organic compound characterized by its pyrazole ring structure, which is a five-membered ring containing two nitrogen atoms. This compound features an ethyl ester functional group and a phenyl substituent, contributing to its chemical reactivity and potential applications. It is typically a white to off-white solid, soluble in organic solvents like ethanol and dichloromethane, but less soluble in water. Ethyl 3-phenyl-1H-pyrazole-5-carboxylate is of interest in various fields, including medicinal chemistry, due to its potential biological activities, such as anti-inflammatory and analgesic properties. The presence of the carboxylate group enhances its reactivity, making it a useful intermediate in organic synthesis. As with many pyrazole derivatives, it may exhibit diverse pharmacological effects, which are subjects of ongoing research. Proper handling and safety measures should be observed, as with all chemical substances, to mitigate any potential hazards associated with its use.

Formula: C₁₂H₁₂N₂O₂

InChI: InChI=1/C12H12N2O2/c1-2-16-12(15)11-8-10(13-14-11)9-6-4-3-5-7-9/h3-8H,2H2,1H3,(H,13,14)

SMILES: CCOC(=O)c1cc(c2ccccc2)[nH]n1

Synonyms:

• 1H-pyrazole-3-carboxylic acid, 5-phenyl-, ethyl ester
• 1H-pyrazole-5-carboxylic acid, 3-phenyl-, ethyl ester
• 5-Phenyl-Pyrazole-3-Carboxylic Acid Ethyl Ester
• ethyl 5-phenyl-1H-pyrazole-3-carboxylate

Ethyl 3-phenyl-1H-pyrazole-5-carboxylate

CAS: 13599-12-7

Formula: C₁₂H₁₂N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 216.2359

Ref: IN-DA007N2U

Ethyl 3-phenyl-1H-pyrazole-5-carboxylate

CAS: 13599-12-7

Ethyl 3-phenyl-1H-pyrazole-5-carboxylate

Purity: 98%

Molecular weight: 216.24g/mol

Ref: 54-OR1005349

Ethyl 3-phenyl-1H-pyrazole-5-carboxylate

CAS: 13599-12-7

Ethyl 3-phenyl-1H-pyrazole-5-carboxylate is a synthetic compound that has been shown to have anticancer activity in lung cancer cells. It inhibits the growth of cancer cells by inducing apoptosis and autophagy. The drug was also found to inhibit xanthine oxidase, which is an enzyme responsible for the production of uric acid, and therefore may be used as a treatment for gout. Ethyl 3-phenyl-1H-pyrazole-5-carboxylate is able to induce apoptosis in lung cancer cells with a dose dependent manner at concentrations of 10 nM - 1 μM. Apoptosis was induced in these cells within 24 hours of exposure, but not at higher doses or after longer periods of exposure.

Formula: C₁₂H₁₂N₂O₂

Purity: Min. 95%

Molecular weight: 216.24 g/mol

Ref: 3D-NAA59912