CAS 1360-76-5
:Ranaconitine
Description:
Ranaconitine, with the CAS number 1360-76-5, is an alkaloid derived from the plant Aconitum, commonly known as monkshood or wolfsbane. This compound is characterized by its complex molecular structure, which includes multiple rings and functional groups typical of alkaloids. Ranaconitine exhibits potent pharmacological properties, particularly in its ability to affect the nervous system, often leading to analgesic and potentially toxic effects. It is known for its high toxicity, which can result in severe physiological responses if ingested improperly. The substance is typically studied for its potential therapeutic applications, but its use is heavily regulated due to safety concerns. In terms of solubility, ranaconitine is generally soluble in organic solvents, but its behavior in aqueous environments can vary. As with many alkaloids, the extraction and purification processes are crucial for obtaining this compound in a usable form for research or medicinal purposes. Overall, ranaconitine represents a significant area of interest in both pharmacology and toxicology.
Formula:C32H44N2O9
InChI:InChI=1S/C32H44N2O9/c1-6-34-16-28(43-26(36)18-9-7-8-10-20(18)33-17(2)35)12-11-24(41-4)31-22-13-19-21(40-3)14-30(38,32(22,39)25(19)42-5)29(37,27(31)34)15-23(28)31/h7-10,19,21-25,27,37-39H,6,11-16H2,1-5H3,(H,33,35)/t19-,21+,22+,23-,24+,25+,27-,28-,29-,30+,31-,32+/m1/s1
InChI key:InChIKey=XTSVKUJYTUPYRJ-FUIAWOLXSA-N
SMILES:O(C)[C@@H]1[C@]23[C@]4([C@](O)(C[C@@]2([C@](OC(=O)C5=C(NC(C)=O)C=CC=C5)(CN4CC)CC1)[H])[C@]6(O)[C@]7(O)[C@]3(C[C@@]([C@@H]7OC)([C@@H](OC)C6)[H])[H])[H]
Synonyms:- (1Alpha,10Alpha,13Alpha,14Alpha,16Beta,17Xi)-20-Ethyl-7,8,9-Trihydroxy-1,14,16-Trimethoxyaconitan-4-Yl 2-(Acetylamino)Benzoate
- (1Alpha,14Alpha,16Beta)-20-Ethyl-7,8,9-Trihydroxy-1,14,16-Trimethoxyaconitan-4-Yl 2-(Acetylamino)Benzoate
- 2H-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine, aconitane-4,7,8,9-tetrol deriv.
- 7-Hydroxylappaconitine
- Aconitane-4,7,8,9-tetrol, 20-ethyl-1,14,16-trimethoxy-, 4-(2-(acetylamino)benzoate), (1alpha,14alpha,16beta)-
- Aconitane-4,7,8,9-tetrol, 20-ethyl-1,14,16-trimethoxy-, 4-[2-(acetylamino)benzoate], (1α,14α,16β)-
- Ranaconitine
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Found 6 products.
ranaconitine
CAS:Ranaconitine is an important diterpenoid alkaloid from Aconitum sinomontanum Nakai,ranaconitine has cardiotoxicity.Formula:C32H44N2O9Purity:98% - 99.02%Color and Shape:SolidMolecular weight:600.7Ranaconitine (>90%)
CAS:Controlled Product<p>Applications Ranaconitine is an important diterpenoid alkaloid from Aconitum sinomontanum and displayspotential anti-inflammatory analgesic activity as well as antagonism and modulation of voltage-gated Na+ channels.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mericli, A. et al.: Helv. Chim. Acta., 95, 314 (2012); Turabekova, M. et al.: Compu. Biol. Chem., 32, 88 (2008);<br></p>Formula:C32H44N2O9Purity:>90%Color and Shape:NeatMolecular weight:600.7Ranaconitine
CAS:Controlled Product<p>Ranaconitine is a diterpenoid alkaloid that can be found in the plants Ranunculus, Isolappula and Aconitum. It has been shown to have an uptake of 0.5-2 µg/cm2/min when applied topically to the skin of mice. Ranaconitine has also been shown to inhibit the growth of bacteria by binding to bacterial DNA gyrase and topoisomerase IV, preventing its replication and transcription. This anti-bacterial activity is reversible and not bactericidal. Ranaconitine has also been shown to have a concentration-time curve with a peak at 2 hours after application on the skin and a plateau between 8-24 hours. The mechanism studies showed that ranaconitine inhibits calcium ion transport through the cell membrane, which leads to inhibition of intracellular ATP production in bacteria.</p>Formula:C32H44N2O9Purity:Min. 95%Molecular weight:600.7 g/mol
