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CAS 136050-67-4

:

fmoc-S-(4-methylbenzyl)-L-cysteine

Description:
Fmoc-S-(4-methylbenzyl)-L-cysteine is a derivative of the amino acid cysteine, characterized by the presence of a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group and a 4-methylbenzyl side chain. This compound is typically used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), where the Fmoc group serves as a protective moiety that can be easily removed under basic conditions. The presence of the sulfur atom in the cysteine residue allows for the formation of disulfide bonds, which are crucial for the stability and functionality of many peptides and proteins. The 4-methylbenzyl group enhances the hydrophobic character of the amino acid, influencing the overall properties of the resulting peptides. Fmoc-S-(4-methylbenzyl)-L-cysteine is valued for its ability to facilitate the synthesis of peptides with specific structural and functional attributes, making it a useful building block in the field of medicinal chemistry and biochemistry. Its CAS number, 136050-67-4, is a unique identifier that aids in the cataloging and procurement of this chemical substance.
Formula:C26H25NO4S
InChI:InChI=1/C26H25NO4S/c1-17-10-12-18(13-11-17)15-32-16-24(25(28)29)27-26(30)31-14-23-21-8-4-2-6-19(21)20-7-3-5-9-22(20)23/h2-13,23-24H,14-16H2,1H3,(H,27,30)(H,28,29)/t24-/m0/s1
SMILES:Cc1ccc(cc1)CSC[C@@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12
Synonyms:
  • Fmoc-Cys(Mbzl)-OH
  • Fmoc-Cys(4-MeBzl)-OH
  • Fmoc-Cys(pMeBzl)-OH
  • N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-(4-methylbenzyl)-L-cysteine
  • Fmoc-Cys(4-Mbzl)-Oh
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