CAS 136098-01-6
:heparin disaccharide iii-H sodium
Description:
Heparin disaccharide III-H sodium, identified by the CAS number 136098-01-6, is a synthetic oligosaccharide derived from heparin, a naturally occurring anticoagulant. This compound consists of a repeating disaccharide unit that typically includes glucuronic acid and N-acetylglucosamine, which are characteristic of heparin's structure. Heparin disaccharides are known for their ability to bind to various proteins, including antithrombin, thereby enhancing its anticoagulant activity. The sodium salt form indicates that the compound is neutralized with sodium ions, which can influence its solubility and stability in biological systems. Heparin disaccharides are often used in research and therapeutic applications, particularly in studies related to blood coagulation, cell signaling, and the development of anticoagulant drugs. Additionally, their structural properties make them valuable in the design of glycosaminoglycan-based therapeutics. Overall, heparin disaccharide III-H sodium exemplifies the complex interplay between structure and biological function in glycosaminoglycans.
Formula:C12H19NNaO13S
InChI:InChI=1/C12H19NO13S.Na/c13-4(2-14)8(18)9(6(17)3-15)25-12-10(26-27(21,22)23)5(16)1-7(24-12)11(19)20;/h1-2,4-6,8-10,12,15-18H,3,13H2,(H,19,20)(H,21,22,23);
InChI key:InChIKey=AFXBIYJDQGMYBC-HSLHGPCSSA-N
SMILES:O([C@@H]([C@@H]([C@H](C=O)N)O)[C@@H](CO)O)[C@H]1[C@H](OS(=O)(=O)O)[C@@H](O)C=C(C(O)=O)O1.[Na]
Synonyms:- <span class="text-smallcaps">D</smallcap>-Glucose, 2-amino-2-deoxy-4-O-(4-deoxy-2-O-sulfo-α-<smallcap>L</span>-threo-hex-4-enopyranuronosyl)-, disodium salt
- hexose, 2-amino-2-deoxy-4-O-(4-deoxy-2-O-sulfohex-4-enopyranuronosyl)-, monosodium salt
- D-Glucose, 2-amino-2-deoxy-4-O-(4-deoxy-2-O-sulfo-α-L-threo-hex-4-enopyranuronosyl)-, disodium salt
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Found 2 products.
Heparin disaccharide III-H disodium salt
CAS:<p>Heparin is a polysaccharide consisting of repeating units of glucosamine and glucuronic acid that has been shown to have anti-coagulant, antithrombotic, and anti-inflammatory properties. Heparin disaccharide III-H disodium salt is a heparin disaccharide that has been modified by the addition of sodium ions. This heparin disaccharide has been shown to inhibit the proliferation of leukaemia cells in vitro, which may be due to its inhibition of DNA synthesis or cell cycle progression. The mechanism by which this heparin disaccharide inhibits cell growth is not yet known. Research into this mechanism could lead to new treatments for cancer and other diseases.</p>Formula:C12H18NNaO13SPurity:Min. 95%Molecular weight:439.33 g/mol
