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CAS 136098-03-8

:

heparin disaccharide iii-S sodium

Description:
Heparin disaccharide III-S sodium, with the CAS number 136098-03-8, is a chemically modified form of heparin, a naturally occurring anticoagulant. This substance is characterized by its structure, which consists of a disaccharide unit derived from heparin, specifically featuring a combination of glucuronic acid and N-acetylglucosamine residues. The "III-S" designation indicates specific sulfation patterns that enhance its biological activity. As a sodium salt, it is soluble in water, making it suitable for various pharmaceutical applications. Heparin disaccharide III-S sodium exhibits anticoagulant properties, primarily by inhibiting thrombin and factor Xa, thus playing a crucial role in preventing blood clot formation. Its use is significant in research and therapeutic contexts, particularly in studies related to cardiovascular health and coagulation disorders. Additionally, the compound's safety profile and efficacy are subjects of ongoing research, contributing to its potential applications in medicine and biotechnology.
Formula:C12H19NNaO16S2
InChI:InChI=1/C12H19NO16S2.Na/c14-2-4(13-30(21,22)23)8(18)9(6(17)3-15)28-12-10(29-31(24,25)26)5(16)1-7(27-12)11(19)20;/h1-2,4-6,8-10,12-13,15-18H,3H2,(H,19,20)(H,21,22,23)(H,24,25,26);
SMILES:C1=C(C(=O)O)OC(C(C1O)OS(=O)(=O)O)OC(C(CO)O)C(C(C=O)NS(=O)(=O)O)O.[Na]
Synonyms:
  • hexose, 2-deoxy-4-O-(4-deoxy-2-O-sulfohex-4-enopyranuronosyl)-2-(sulfoamino)-, monosodium salt
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