CAS 1361110-64-6

3,4-Dihydro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-1,4-benzoxazine

Description:

3,4-Dihydro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-1,4-benzoxazine is a chemical compound characterized by its unique structural features, which include a benzoxazine ring and a dioxaborolane moiety. The presence of the dioxaborolane group suggests potential applications in organoboron chemistry, particularly in cross-coupling reactions and as a building block for various organic syntheses. The compound's benzoxazine structure contributes to its stability and may impart specific electronic properties, making it of interest in materials science and medicinal chemistry. Additionally, the tetramethyl substituents enhance its steric bulk, which can influence reactivity and solubility. The compound is likely to exhibit moderate to low solubility in polar solvents due to its hydrophobic characteristics, while its boron content may allow for coordination with various ligands. Overall, this compound's unique combination of functional groups positions it as a versatile intermediate in synthetic organic chemistry and potential applications in drug development or polymer science.

Formula: C₁₄H₂₀BNO₃

InChI: InChI=1S/C14H20BNO3/c1-13(2)14(3,4)19-15(18-13)10-5-6-11-12(9-10)17-8-7-16-11/h5-6,9,16H,7-8H2,1-4H3

InChI key: InChIKey=AUGHRUKXHXNOCW-UHFFFAOYSA-N

SMILES: CC1(C)OB(OC1(C)C)C=2C=C3C(=CC2)NCCO3

Synonyms:

• 2H-1,4-Benzoxazine, 3,4-dihydro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
• 3,4-Dihydro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-1,4-benzoxazine

2H-1,4-Benzoxazine, 3,4-dihydro-7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-

CAS: 1361110-64-6

Formula: C₁₄H₂₀BNO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 261.1245

Ref: IN-DA009CS3

7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine

CAS: 1361110-64-6

7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine

Purity: 95%

Molecular weight: 261.12g/mol

Ref: 54-OR82287

7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine

CAS: 1361110-64-6

Formula: C₁₄H₂₀BNO₃

Purity: 95%

Color and Shape: Liquid, No data available.

Molecular weight: 261.13

Ref: 10-F322865

3,4-Dihydro-2H-1,4-benzoxazine-7-boronic Acid Pinacol Ester

Controlled Product

CAS: 1361110-64-6

Applications 3,4-Dihydro-2H-1,4-benzoxazine-7-boronic acid pinacol ester is a useful intermediate for the synthesis of naphthamides which functions as VEGFR-2 kinase inhibitors for cancer treatment.
References Lv, Y., et al.: ACS Med. Chem. Lett., 5, 592 (2014)

Formula: C₁₄H₂₀BNO₃

Color and Shape: Neat

Molecular weight: 261.12

Ref: TR-D454873

3,4-Dihydro-2H-benzo[b][1,4]oxazine-7-boronic acid pinacol ester

CAS: 1361110-64-6

Versatile small molecule scaffold

Formula: C₁₄H₂₀BNO₃

Purity: Min. 95%

Molecular weight: 261.12 g/mol

Ref: 3D-LEC11064