CAS 136112-01-1

Salmeterol-fluticasone propionate mixt.

Description:

Salmeterol-fluticasone propionate mixture is a combination medication primarily used in the management of asthma and chronic obstructive pulmonary disease (COPD). Salmeterol is a long-acting beta-agonist (LABA) that works by relaxing the muscles in the airways, leading to improved airflow and easier breathing. Fluticasone propionate, on the other hand, is a corticosteroid that reduces inflammation in the airways, helping to prevent asthma attacks and manage symptoms. The combination of these two active ingredients allows for both immediate relief of bronchospasm and long-term control of airway inflammation. This dual-action approach enhances therapeutic efficacy, making it particularly beneficial for patients with persistent respiratory conditions. The formulation is typically delivered via inhalation, ensuring targeted action in the lungs. As with any medication, it is important to use it as prescribed and be aware of potential side effects, which may include throat irritation, headache, or increased heart rate. Regular monitoring and consultation with a healthcare provider are essential for optimal management of respiratory conditions.

Formula: C₂₅H₃₇NO₄·C₂₅H₃₁F₃O₅S

InChI: InChI=1S/C25H31F3O5S.C25H37NO4/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4;27-20-23-18-22(13-14-24(23)28)25(29)19-26-15-7-1-2-8-16-30-17-9-6-12-21-10-4-3-5-11-21/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3;3-5,10-11,13-14,18,25-29H,1-2,6-9,12,15-17,19-20H2/t13-,15+,16+,18+,19+,22+,23+,24+,25+;/m1./s1

InChI key: InChIKey=YYAZJTUGSQOFHG-RZFXJYHSSA-N

SMILES: C(CNCCCCCCOCCCCC1=CC=CC=C1)(O)C2=CC(CO)=C(O)C=C2.O(C(CC)=O)[C@@]1(C(SCF)=O)[C@]2(C)[C@@](C[C@H]1C)([C@]3([C@](F)([C@@H](O)C2)[C@]4(C)C([C@@H](F)C3)=CC(=O)C=C4)[H])[H]

Synonyms:

• (6Α,11Β,16Α,17Α)-6,9-Difluoro-17-{[(Fluoromethyl)Sulfanyl]Carbonyl}-11-Hydroxy-16-Methyl-3-Oxoandrosta-1,4-Dien-17-Yl Propanoate - 2-(Hydroxymethyl)-4-(1-Hydroxy-2-{[6-(4-Phenylbutoxy)Hexyl]Amino}Ethyl)Phenol (1:1)
• Adoair
• Adoair Diskus
• Advair
• Advair Diskus
• Airexar Spiromax
• Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-, S-(fluoromethyl) ester, (6α,11β,16α,17α)-, mixt. with 4-hydroxy-α¹-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol
• Flutide Diskus
• Salmeterol-fluticasone propionate mixt.
• Seretide
• Seretide Accuhaler
• [(6S,8S,10S,11S,13S,14S,16R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate

Seretide

CAS: 136112-01-1

Seretide, a combination of fluticasone and salmeterol, controls symptoms of asthma and chronic obstructive pulmonary disease (COPD).

Formula: C₅₀H₆₈F₃NO₉S

Purity: 98%

Color and Shape: Solid

Molecular weight: 916.15

Ref: TM-TP2406

Salmeterol fluticasone propionate

Controlled Product

CAS: 136112-01-1

Salmeterol fluticasone propionate is a medicinal product that is used to treat respiratory disorders such as asthma and chronic obstructive pulmonary disease (COPD). It contains two active ingredients, salmeterol and fluticasone propionate. Salmeterol works by relaxing the muscles in the airways, while fluticasone propionate reduces inflammation in the lungs. This combination medication has been shown to improve lung function and reduce symptoms of wheezing and shortness of breath.

Formula: C₅₀H₆₈F₃NO₉S

Purity: Min. 95%

Molecular weight: 916.1 g/mol

Ref: 3D-LFA11201