Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide that plays a significant role in various physiological processes, including neuroprotection, neurotransmission, and hormone secretion. The substance associated with the CAS number 136134-68-4 is a synthetic form of PACAP, which is known for its ability to activate adenylate cyclase, leading to increased levels of cyclic AMP (cAMP) in target cells. This mechanism is crucial for mediating various cellular responses, including those related to stress, circadian rhythms, and immune function. PACAP is also involved in the regulation of vascular tone and has neurotrophic effects, promoting the survival and differentiation of neurons. Its diverse biological activities make it a subject of interest in research related to neurodegenerative diseases, metabolic disorders, and potential therapeutic applications. The peptide is typically characterized by its high solubility in aqueous solutions and its sensitivity to enzymatic degradation, necessitating careful handling and storage conditions to maintain its stability and activity.

PITUITARY ADENYLATE CYCLASE ACTIVATING

136134-68-4: Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide that plays a significant role in various physiological processes, including neuroprotection, neurotransmission, and hormone secretion. The substance associated with the CAS number 136134-68-4 is a synthetic form of PACAP, which is known for its ability to activate adenylate cyclase, leading to increased levels of cyclic AMP (cAMP) in target cells. This mechanism is crucial for mediating various cellular responses, including those related to stress, circadian rhythms, and immune function. PACAP is also involved in the regulation of vascular tone and has neurotrophic effects, promoting the survival and differentiation of neurons. Its diverse biological activities make it a subject of interest in research related to neurodegenerative diseases, metabolic disorders, and potential therapeutic applications. The peptide is typically characterized by its high solubility in aqueous solutions and its sensitivity to enzymatic degradation, necessitating careful handling and storage conditions to maintain its stability and activity.

CAS 136134-68-4

PITUITARY ADENYLATE CYCLASE ACTIVATING

PACAP (6-27), Human, Ovine, Rat

Ref: 02-J66872

PACAP-27 (6-27) (human, chicken, mouse, ovine, porcine, rat)

Ref: 3D-VAC-00014