CymitQuimica logo

CAS 136145-07-8

:

Arofylline

Description:
Arofylline, identified by its CAS number 136145-07-8, is a chemical compound that belongs to the class of xanthine derivatives. It is primarily recognized for its potential as a bronchodilator, which means it may help to relax and widen the air passages in the lungs, making it useful in treating respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). Arofylline exhibits anti-inflammatory properties, which can further aid in alleviating symptoms associated with airway inflammation. The compound's mechanism of action typically involves the inhibition of phosphodiesterase enzymes, leading to increased levels of cyclic AMP in cells, which promotes relaxation of smooth muscle. Additionally, Arofylline may have a favorable pharmacokinetic profile, contributing to its therapeutic efficacy. However, as with any pharmacological agent, the safety and side effects must be carefully considered, and its use should be guided by clinical evidence and regulatory approvals. Further research may be necessary to fully elucidate its potential applications and benefits in clinical settings.
Formula:C14H13ClN4O2
InChI:InChI=1S/C14H13ClN4O2/c1-2-7-18-13(20)11-12(17-8-16-11)19(14(18)21)10-5-3-9(15)4-6-10/h3-6,8H,2,7H2,1H3,(H,16,17)
InChI key:InChIKey=GVTLDPJNRVMCAL-UHFFFAOYSA-N
SMILES:O=C1N(C2=C(C(=O)N1CCC)NC=N2)C3=CC=C(Cl)C=C3
Synonyms:
  • Arofylline
  • 1H-Purine-2,6-dione, 3-(4-chlorophenyl)-3,9-dihydro-1-propyl-
  • 3-(p-Chlorophenyl)-1-propylxanthine
  • Arofyllin
  • 3-(4-chlorophenyl)-1-propyl-3,7-dihydro-1H-purine-2,6-dione
  • LAS 31025
  • Arofyllin [USAN]
  • 1H-Purine-2,6-dione, 3-(4-chlorophenyl)-3,7-dihydro-1-propyl-
  • 3-(4-Chlorophenyl)-3,9-dihydro-1-propyl-1H-purine-2,6-dione
  • LAS 31025
  • See more synonyms
Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 2 products.
  • Arofylline

    CAS:
    <p>Arofylline</p>
    Purity:≥95%
    Molecular weight:304.73g/mol

    Ref: 54-BUP01180

    1mg
    268.00€
    5mg
    581.00€
    10mg
    843.00€
    25mg
    1,188.00€
    50mg
    1,662.00€
  • Arofylline

    CAS:
    <p>Arofylline (LAS 31025) is a PDE4 inhibitor and can be used for asthma studies.</p>
    Formula:C14H13ClN4O2
    Purity:98.19%
    Color and Shape:Solid
    Molecular weight:304.73