CAS 1361569-18-7

6-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl) -7-methyl-7,9-dihydro-8H-purin-8-one

Description:

6-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-7-methyl-7,9-dihydro-8H-purin-8-one is a complex organic compound characterized by its multi-ring structure, which includes a purine base and a pyrazolo-pyridine moiety. This compound features an amino group and a fluorobenzyl substituent, contributing to its potential biological activity. The presence of the fluorine atom may enhance lipophilicity and influence the compound's interaction with biological targets. The purine core is known for its role in nucleic acids and various biochemical processes, while the pyrazolo-pyridine structure is often associated with pharmacological properties. This compound may exhibit properties such as enzyme inhibition or receptor modulation, making it of interest in medicinal chemistry and drug development. Its specific solubility, stability, and reactivity would depend on the surrounding conditions, including pH and solvent polarity. Overall, this compound represents a class of heterocyclic compounds that could have significant implications in therapeutic applications.

Formula: C₁₉H₁₅FN₈O

Synonyms:

• Riociguat-11
• 6-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl) -7-methyl-7,9-dihydro-8H-purin-8-one
• RiociguatImpurity13LithiumSalt
• Riociguat Impurity 17/6-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl) -7-methyl-7,9-dihydro-8H-purin-8-one
• 6-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo

Riociguat Impurity 18

CAS: 1361569-18-7

Formula: C₁₉H₁₅FN₈O

Molecular weight: 390.4

Ref: ST-EA-CP-R35016

Riociguat Impurity 13 Lithium Salt

CAS: 1361569-18-7

Formula: C₁₉H₁₄FN₈O·Li

Color and Shape: White To Off-White Solid

Molecular weight: 389.37 6.94

Ref: 4Z-R-080018

Methyl-dihydropurinone

Controlled Product

CAS: 1361569-18-7

Applications Methyl-dihydropurinone is an impurity of Riociguat (R520000). Riociguat is used in the treatment for pulmonary hypertension.
References Frey, R. et al.: J. Clin. Pharmacol., 51, 1051 (2011)

Formula: C₁₉H₁₅FN₈O

Color and Shape: Neat

Molecular weight: 390.374

Ref: TR-M226215

Methyl-dihydropurinone

CAS: 1361569-18-7

Methyl-dihydropurinone is an impurity in a drug product. It has been used as an analytical standard for the identification and quantification of metabolites of drugs and other compounds. The purity of this compound is >98%. It is also used as a pharmacopoeia standard for HPLC analysis. This compound is synthetically produced by custom synthesis. Methyl-dihydropurinone has been found to be metabolized into methyl-dihydropyrimidine, which can be detected using HPLC with UV detection at 254 nm.

Formula: C₁₉H₁₅FN₈O

Purity: Min. 95%

Molecular weight: 390.4 g/mol

Ref: 3D-LEC56918