CAS 136247-18-2

N-(p-Nitrophenethyl)spiperone

Description:

N-(p-Nitrophenethyl)spiperone is a chemical compound that belongs to the class of spiperone derivatives, which are known for their pharmacological properties, particularly in relation to dopamine receptor antagonism. This compound features a spiperone backbone, which is characterized by a piperidine ring and a phenyl group, modified by the addition of a p-nitrophenethyl group. The presence of the nitro group on the phenethyl moiety enhances its lipophilicity and may influence its biological activity. N-(p-Nitrophenethyl)spiperone is primarily studied for its potential applications in neuroscience and psychopharmacology, particularly in the context of research on schizophrenia and other psychiatric disorders. Its interactions with neurotransmitter systems, especially dopamine and serotonin receptors, make it a compound of interest in drug development. As with many chemical substances, safety and handling precautions are essential due to its potential biological effects. Further research is necessary to fully elucidate its pharmacokinetics, mechanisms of action, and therapeutic potential.

Formula: C₃₁H₃₃FN₄O₄

InChI: InChI=1/C31H33FN4O4/c32-26-12-10-25(11-13-26)29(37)7-4-19-33-21-17-31(18-22-33)30(38)34(23-35(31)27-5-2-1-3-6-27)20-16-24-8-14-28(15-9-24)36(39)40/h1-3,5-6,8-15H,4,7,16-23H2

SMILES: c1ccc(cc1)N1CN(CCc2ccc(cc2)N(=O)=O)C(=O)C21CCN(CCCC(=O)c1ccc(cc1)F)CC2

Synonyms:

• 8-[4-(4-Fluorophenyl)-4-oxobutyl]-3-[2-(4-nitrophenyl)ethyl]-1-phenyl- 1,3,8-triazaspiro[4.5]decan-4-one

N-(p-Nitrophenethyl)spiperone

Controlled Product

CAS: 136247-18-2

Applications Analogue of Spiperone.
References Chivers, J., et al.: Br. J. Pharmacol., 90, 467 (1987), Lever, J.R., et al.: Life Sci., 46, 1967 (1990),

Formula: C₃₁H₃₃FN₄O₄

Color and Shape: Neat

Molecular weight: 544.62

Ref: TR-N496940