CAS 136310-93-5
:Tiotropium bromide
Description:
Tiotropium bromide is a long-acting anticholinergic medication primarily used in the management of chronic obstructive pulmonary disease (COPD) and asthma. It functions as a bronchodilator by inhibiting the action of acetylcholine on muscarinic receptors in the airways, leading to relaxation of smooth muscles and improved airflow. The substance is typically administered via inhalation, allowing for localized effects in the lungs while minimizing systemic exposure. Tiotropium bromide is characterized by its high affinity for M3 muscarinic receptors, which are predominantly found in the bronchial tissues. It has a prolonged duration of action, allowing for once-daily dosing, which enhances patient compliance. The compound is a white to off-white powder, soluble in water, and has a molecular weight that supports its pharmacological activity. Its safety profile is generally favorable, with common side effects including dry mouth and potential cardiovascular effects, necessitating monitoring in patients with pre-existing conditions. Overall, tiotropium bromide represents a significant advancement in the treatment of respiratory diseases, improving quality of life for many patients.
Formula:C19H22NO4S2·Br
InChI:InChI=1/C19H22NO4S2.BrH/c1-20(2)12-9-11(10-13(20)17-16(12)24-17)23-18(21)19(22,14-5-3-7-25-14)15-6-4-8-26-15;/h3-8,11-13,16-17,22H,9-10H2,1-2H3;1H/q+1;/p-1/t11-,12-,13+,16-,17+;
InChI key:InChIKey=DQHNAVOVODVIMG-FOGIBKMMNA-M
SMILES:C(C(O[C@H]1C[C@]2([C@]3([C@@]([C@@](C1)([N+]2(C)C)[H])(O3)[H])[H])[H])=O)(O)(C4=CC=CS4)C5=CC=CS5.[Br-]
Synonyms:- (1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane bromide
- (1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane bromide hydrate (1:1:1)
- (1R,2S,4R,5S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane bromide
- (1a,2,4,5a,7)-7-[(2-Hydroxy-2,2-di-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide
- (1a,2b,4b,5a,7b)-7-[(Hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide
- (1Α,2Β,4Β,5Α,7Β
- (1α,2β,4β,5α,7β)-7-[(Hy-droxydi-2-thienylacetyl)axy]-9,9-dimethyl-3-oxa-9-azoniatri-cyclo[3.3.1.02.4]nonane
- (1α,2β,4β,5α,7β)-7-[(Hydroxydi-2-thienylacetyl)oxy]-9,9-di-methyl-3-oxa-9-azoniatricyclo[3.3.1.0]nonane bromide
- 3-Oxa-9-azatricyclo[3.3.1.0<sup>2,4</sup>]nonane, 3-oxa-9-azoniatricyclo[3.3.1.0<sup>2,4</sup>]nonane deriv.
- 3-Oxa-9-azoniatricyclo(3,3.1.0(2,4))nonane, 7-((hydroxydi-2-thienylacetyl)oxy)-9,9-dimethyl-, bromide, (1alpha,2beta,4beta,5alpha,7beta)-
- 3-Oxa-9-azoniatricyclo[3.3.1.0<sup>2,4</sup>]nonane, 7-[(2-hydroxy-2,2-di-2-thienylacetyl)oxy]-9,9-dimethyl-, bromide (1:1), (1α,2β,4β,5α,7β)-
- 3-Oxa-9-azoniatricyclo[3.3.1.0<sup>2,4</sup>]nonane, 7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-, bromide, (1α,2β,4β,5α,7β)-
- 6b,7b-Epoxy-3b-hydroxy-8-methyl-1aH,5aH-tropanium bromide di-2-thienylglycolate
- 7-((Hydroxybis(2-thienyl)acetyl)oxy)-9,9-dimethyl-3-oxa-9-azoniatricyclo(3.3.1.0(2,4))nonane bromide
- 7-{[Hydroxy(Dithiophen-2-Yl)Acetyl]Oxy}-9,9-Dimethyl-3-Oxa-9-Azoniatricyclo[3.3.1.0~2,4~]Nonane Bromide Hydrate (1:1:1)
- Anhydrous Tiotropium bromide
- Ba 679Br
- Spiriva
- Spiriva Handihaler
- Tiopropium
- 3-Oxa-9-azatricyclo[3.3.1.02,4]nonane, 3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane deriv.
- Tiotropium bromide
- 3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 7-[(2-hydroxy-2,2-di-2-thienylacetyl)oxy]-9,9-dimethyl-, bromide (1:1), (1α,2β,4β,5α,7β)-
- See more synonyms
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Found 13 products.
Tiotropium Bromide
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C19H22BrNO4S2Color and Shape:White Light Yellow PowderMolecular weight:471.01736(1R,2R,4S,5S,7R)-7-{[2-hydroxy-2,2-bis(thiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.0^{2,4}]nonan-9-ium bromide
CAS:Formula:C19H22BrNO4S2Purity:98%Color and Shape:SolidMolecular weight:472.4163Tiotropium bromide
CAS:<p>Tiotropium bromide (BA679 BR) is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD).</p>Formula:C19H22BrNO4S2Purity:96.82% - 99.97%Color and Shape:White SolidMolecular weight:472.42Tiotropium Bromide
CAS:Formula:C19H22NO4S2·BrColor and Shape:White To Off-White SolidMolecular weight:392.51 79.90Tiotropium Bromide
CAS:Formula:C19H22BrNO4S2Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:472.41Tiotropium Bromide
CAS:Formula:C19H22NO4S2·BrColor and Shape:White To Off-WhiteMolecular weight:472.42Tiotropium bromide
CAS:<p>Muscarinic antagonist; bronchodilator</p>Formula:C19H22BrNO4S2Purity:Min. 95%Color and Shape:PowderMolecular weight:472.42 g/molTiotropium bromide - Bio-X ™
CAS:<p>Tiotropium is a bronchodilator that is used for the management of chronic obstructive pulmonary disease or COPD. It is an antimuscarinic drug that also treats asthma. Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation.</p>Formula:C19H22BrNO4S2Purity:Min. 95%Color and Shape:PowderMolecular weight:472.42 g/molTiotropium-d6 Bromide
CAS:Controlled ProductFormula:C19H16D6BrNO4S2Color and Shape:White To PurpleMolecular weight:478.45
![(1R,2R,4S,5S,7R)-7-{[2-hydroxy-2,2-bis(thiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azatricyclo[…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0011M7.jpg&w=3840&q=75)
