CAS 1363173-34-5

1-Methyl-1H-indazole-3-carboxylic Acid Anhydride

Description:

1-Methyl-1H-indazole-3-carboxylic Acid Anhydride is a chemical compound characterized by its unique structure, which includes an indazole ring fused with a carboxylic acid anhydride functional group. This compound typically exhibits properties associated with both indazole derivatives and anhydrides, such as reactivity towards nucleophiles due to the electrophilic nature of the anhydride carbonyl groups. It is likely to be a solid at room temperature, with potential applications in organic synthesis, particularly in the development of pharmaceuticals or agrochemicals. The presence of the methyl group on the indazole ring can influence its solubility and reactivity, making it a versatile intermediate in chemical reactions. Additionally, the compound may exhibit specific spectral characteristics in techniques such as NMR and IR spectroscopy, aiding in its identification and characterization. As with many anhydrides, it may also be sensitive to moisture, leading to hydrolysis and the formation of the corresponding carboxylic acid. Proper handling and storage conditions are essential to maintain its stability and reactivity.

Formula: C₁₈H₁₄N₄O₃

Synonyms:

• 1-methyl-1H-indazole-3-carboxylic anhydride
• Granisetron anhydride Impurity
• Granisetron EP impurity I
• 1-Methyl-1H-indazole-3-carboxylic Acid Anhydride
• 1H-Indazole-3-carboxylic acid, 1-methyl-, 3,3'-anhydride
• Granisetron Impurity 9（Granisetron EP Impurity I）
• WXKUAYVKUKAIQR-UHFFFAOYSA-N
• Imp. I (EP):1-Methyl-1H-indazole-3-carboxylicAnhydride

Granisetron EP Impurity I

CAS: 1363173-34-5

Formula: C₁₈H₁₄N₄O₃

Color and Shape: White To Off-White Solid

Molecular weight: 334.34

Ref: 4Z-G-077

1-Methyl-1H-indazole-3-carboxylic Anhydride

CAS: 1363173-34-5

Color and Shape: Neat

Ref: 86-MM0398.09

1-Methyl-1H-indazole-3-carboxylic Acid Anhydride

Controlled Product

CAS: 1363173-34-5

Applications 1-Methyl-1H-indazole-3-carboxylic Acid Anhydride is an impurity of Granisetron (G780000), a specific serotonin (5HT3) receptor antagonist and a antiemetic agent.
References Kilpatrick, G.J., et al.: Nature, 330, 746 (1987); Durig, T., et al.: J. Pharm. Sci., 86, 1092 (1997); Yuasa, H., et al.: Chem. Pharm. Bull., 44, 1361 (1996); Vishnu, E.V.R., et al.: Lett. Org. Chem., 8, 722 (2011);

Formula: C₁₈H₁₄N₄O₃

Color and Shape: Off-White

Molecular weight: 334.33

Ref: TR-M313465

Granisetron EP Impurity I

CAS: 1363173-34-5

Formula: C₁₈H₁₄N₄O₃

Molecular weight: 334.33

Ref: ST-EA-CP-G16009

1-Methyl-1H-indazole-3-carboxylic acid anhydride

Controlled Product

CAS: 1363173-34-5

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Formula: C₁₈H₁₄N₄O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 334.3 g/mol

Ref: 3D-NEC17334