CAS 136381-85-6

2-[[[4-(2-Chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-acetic acid

Description:

2-[[[4-(2-Chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-acetic acid, with CAS number 136381-85-6, is a synthetic organic compound characterized by its complex structure, which includes an indole moiety, a thiazole ring, and a chlorophenyl group. This compound typically exhibits properties such as moderate solubility in organic solvents and limited solubility in water, which is common for many indole derivatives. It may possess biological activity, potentially acting as an inhibitor or modulator in various biochemical pathways, making it of interest in pharmaceutical research. The presence of functional groups such as amine and carboxylic acid suggests it could engage in hydrogen bonding, influencing its reactivity and interaction with biological targets. Additionally, the chlorophenyl and thiazole components may contribute to its lipophilicity and overall pharmacokinetic profile. As with many compounds in medicinal chemistry, its efficacy and safety would need to be evaluated through rigorous testing.

Formula: C₂₀H₁₄ClN₃O₃S

InChI: InChI=1S/C20H14ClN3O3S/c21-14-7-3-2-6-13(14)15-11-28-20(22-15)23-19(27)17-9-12-5-1-4-8-16(12)24(17)10-18(25)26/h1-9,11H,10H2,(H,25,26)(H,22,23,27)

InChI key: InChIKey=ILNRQFBVVQUOLP-UHFFFAOYSA-N

SMILES: C(C(O)=O)N1C=2C(C=C1C(NC3=NC(=CS3)C4=C(Cl)C=CC=C4)=O)=CC=CC2

Synonyms:

• (2-{[4-(2-chlorophenyl)-1,3-thiazol-2-yl]carbamoyl}-1H-indol-1-yl)acetic acid
• 1H-Indole-1-acetic acid, 2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]carbonyl]-
• 2-(2-((4-(2-Chlorophenyl)thiazol-2-yl)carbamoyl)-1H-indol-1-yl)acetic acid
• 2-[2-[[4-(2-Chlorophenyl)-1,3-thiazol-2-yl]carbamoyl]indol-1-yl]acetic acid hydrate
• 2-[[N-[4-(2-Chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-acetic acid
• 2-[[[4-(2-Chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-acetic acid
• Lintitript
• Sr 27897B
• Sr-27897
• [2-[4-(2-Chloro-phenyl)-thiazol-2-ylcarbamoyl]-indol-1-yl]-acetic acid

1H-Indole-1-acetic acid, 2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]carbonyl]-

CAS: 136381-85-6

Formula: C₂₀H₁₄ClN₃O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 411.8615

Ref: IN-DA0011TB

Lintitript

CAS: 136381-85-6

Lintitript

Purity: ≥98%

Molecular weight: 411.86g/mol

Ref: 54-BUP16244

Lintitript

CAS: 136381-85-6

Lintitript (SR 27897) is a selective antagonist of CCK1 with EC50s of 6 nM and 200 nM for CCK1 and CCK2. The Ki value is 0.2 nM for CCK1.

Formula: C₂₀H₁₄ClN₃O₃S

Purity: 99.28%

Color and Shape: Solid

Molecular weight: 411.86

Ref: TM-T15759

SR 27897 hydrate

CAS: 136381-85-6

Formula: C₂₀H₁₄ClN₃O₃S·xH₂O

Molecular weight: 411.86 (anhydrous)

Ref: 7W-GK4410

SR 27897

Controlled Product

CAS: 136381-85-6

SR 27897 is a novel, non-peptide, orally active agent that selectively activates the receptor for substance P. Animal studies have shown that SR 27897 has a hypoglycemic effect and can reduce food intake. The drug binds to the receptor for substance P and inhibits the release of acetylcholine from nerve terminals in the bladder, which may be due to its ability to release melatonin from pineal gland cells. It is also thought that SR 27897 may have therapeutic potential in treating cancer.

Formula: C₂₀H₁₄ClN₃O₃S

Purity: Min. 95%

Molecular weight: 411.86 g/mol

Ref: 3D-LFA38185