CAS 136398-54-4

alisamycin

Description:

Alisamycin is a naturally occurring antibiotic that belongs to the class of compounds known as macrolides. It is produced by certain strains of the bacterium Streptomyces, which are known for their ability to synthesize a wide variety of bioactive secondary metabolites. Alisamycin exhibits antibacterial properties, particularly against Gram-positive bacteria, making it of interest in the field of medicinal chemistry and pharmacology. The compound's mechanism of action typically involves inhibition of protein synthesis, which is a common feature among macrolide antibiotics. Alisamycin has also been studied for its potential antitumor activity, adding to its significance in cancer research. Its chemical structure features a large lactone ring, which is characteristic of macrolides, and it may contain various functional groups that contribute to its biological activity. As with many antibiotics, the development of resistance is a concern, prompting ongoing research into its efficacy and potential modifications to enhance its therapeutic profile.

Formula: C₂₉H₃₂N₂O₇

InChI: InChI=1/C29H32N2O7/c32-21-15-16-22(33)25(21)31-24(35)13-6-1-2-9-17-29(37)18-20(26(36)27-28(29)38-27)30-23(34)14-8-7-12-19-10-4-3-5-11-19/h1-2,6-9,12-14,17-19,27-28,32,37H,3-5,10-11,15-16H2,(H,30,34)(H,31,35)/b2-1+,12-7+,13-6+,14-8+,17-9+

Synonyms:

• 3-[[(2E,4E)-5-Cyclohexyl-1-oxo-2,4-pentadienyl]amino]-5-hydroxy-5-[(1E,3E,5E)-7-(2-hydroxy-5-oxo-1-cyclopentenylamino)-7-oxo-1,3,5-heptatrienyl]-7-oxabicyclo[4.1.0]hept-3-en-2-one
• Alisamycin
• (2E,4E,6E)-7-(4-{[(2E,4E)-5-cyclohexylpenta-2,4-dienoyl]amino}-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-2-yl)-N-(2-hydroxy-5-oxocyclopent-1-en-1-yl)hepta-2,4,6-trienamide
• 2,4,6-Heptatrienamide, 7-(4-((5-cyclohexyl-1-oxo-2,4-pentadienyl)amino)-2-hydroxy-5-oxo-7-oxabicyclo(4.1.0)hept-3-en-2-yl)-N-(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-
• 2,4,6-Heptatrienamide, 7-[(1S,2R,6R)-4-[[(2E,4E)-5-cyclohexyl-1-oxo-2,4-pentadien-1-yl]amino]-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-2-yl]-N-(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-, (2E,4E,6E)-
• 2,4,6-Heptatrienamide, 7-(4-((5-cyclohexyl-1-oxo-2,4-pentadienyl)amino)-2-hydroxy-5-oxo-7-oxobicyclo(4.2.0)hept-3-en-2-yl)-N-(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-
• alisamycin

Alisamycin

CAS: 136398-54-4

Alisamycin is an antibiotic belonging to the hemonycin class. It exhibits activity against gram-positive bacteria and fungi, and also possesses mild antitumor properties.

Formula: C₂₉H₃₂N₂O₇

Color and Shape: Solid

Molecular weight: 520.574

Ref: TM-TN8987