CAS 136431-94-2

7-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-diMethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane BroMide

Description:

The chemical substance known as "7-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-diMethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide," with the CAS number 136431-94-2, is a complex organic compound characterized by its unique structural features. It contains a bicyclic framework, which is indicative of its tricyclic nature, and incorporates both thienyl and hydroxy functional groups, contributing to its potential reactivity and solubility properties. The presence of a quaternary ammonium group (indicated by the "9-azoniatricyclo" part of the name) suggests that the compound may exhibit ionic characteristics, influencing its interaction with biological systems and its solubility in polar solvents. The bromide counterion indicates that it is likely to be a salt, which can affect its stability and bioavailability. Overall, this compound may possess interesting pharmacological properties, making it a candidate for further research in medicinal chemistry and related fields. However, specific biological activity and applications would require empirical investigation.

Formula: C₁₉H₂₂BrNO₄S₂

Synonyms:

• 7-(2-hydroxy-2-(thiophen-2-yl)-2-(thiophen-3-yl)acetoxy)-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-9-ium bromide
• 7-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-dimethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bro
• 7-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-diMethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane BroMide
• BALCMZZLILDTJR-UHFFFAOYSA-M
• Iso TiotropiuM BroMide IMpurity

7-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-dimethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide

Controlled Product

CAS: 136431-94-2

Applications 7-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-dimethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide is an impurity in the synthesis of Tiotropium Bromide (T444850), a muscarinic receptor antagonist. Bronchodilator.
References Rodgers, T. et al.: J. Med. Chem., 20, 591 (1977); Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006);

Formula: C₁₉H₂₂BrNO₄S₂

Color and Shape: Neat

Molecular weight: 472.42

Ref: TR-H962025

7-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-dimethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide-d6

Controlled Product

CAS: 136431-94-2

Applications Isotope labelled 7-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-dimethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide is an impurity in the synthesis of Tiotropium Bromide (T444850), a muscarinic receptor antagonist. Bronchodilator.
References Rodgers, T. et al.: J. Med. Chem., 20, 591 (1977); Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006);

Formula: C₁₉D₆H₁₆NO₄S₂

Color and Shape: Off-White

Molecular weight: 398.549

Ref: TR-H962027

Iso Tiotropium Bromide

CAS: 136431-94-2

Formula: C₁₉H₂₂NO₄S₂Br

Molecular weight: 392.51 : 79.9

Ref: ST-EA-CP-T22010