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CAS 136434-34-9

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Duloxetine hydrochloride

Description:
Duloxetine hydrochloride is a pharmaceutical compound primarily used as an antidepressant and for the treatment of generalized anxiety disorder, fibromyalgia, and chronic pain conditions. It belongs to the class of serotonin-norepinephrine reuptake inhibitors (SNRIs), which function by increasing the levels of serotonin and norepinephrine in the brain, thereby enhancing mood and alleviating pain. The substance is typically administered in oral form and is known for its relatively rapid onset of action compared to some other antidepressants. Duloxetine hydrochloride is characterized by its white to off-white crystalline powder form, with a molecular formula that reflects its complex structure. It is soluble in water and exhibits a moderate pH range, which is important for its formulation and stability. Common side effects may include nausea, dry mouth, and fatigue, and it is essential to monitor patients for potential interactions with other medications. Overall, duloxetine hydrochloride plays a significant role in managing various mental health and pain-related disorders.
Formula:C18H19NOS·ClH
InChI:InChI=1S/C18H19NOS.ClH/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16;/h2-10,13,17,19H,11-12H2,1H3;1H/t17-;/m0./s1
InChI key:InChIKey=BFFSMCNJSOPUAY-LMOVPXPDSA-N
SMILES:O([C@@H](CCNC)C1=CC=CS1)C=2C3=C(C=CC2)C=CC=C3.Cl
Synonyms:
  • (3R)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-aminium chloride
  • (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine hydrochloride (1:1)
  • (RS)-N-Methyl-gama-(1-naphthalenyloxy)-2-thiophenepropanamine hydrochloride
  • (S)-(+)-Duloxetine hydrochloride
  • (S)-(+)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine hydrochloride
  • (S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine hydrochloride
  • (S)-γ-(1-Naphthalenoxy)-N-methylthiophene-2-propanamine monohydrochloride
  • 2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, hydrochloride (1:1), (γS)-
  • 2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, hydrochloride, (S)-
  • 2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, hydrochloride, (γS)-
  • See more synonyms
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