CAS 136468-36-5

Foropafant

Description:

Foropafant, with the CAS number 136468-36-5, is a chemical compound that has been studied primarily for its potential therapeutic applications. It is classified as a selective antagonist of the neurokinin-1 (NK1) receptor, which is involved in various physiological processes, including pain perception, stress response, and the regulation of mood. The compound's mechanism of action involves blocking the binding of substance P, a neuropeptide associated with pain and inflammation, to its receptor. This characteristic makes Foropafant a candidate for research in the treatment of conditions such as anxiety, depression, and chronic pain. In terms of its physical properties, Foropafant is typically characterized by its molecular structure, which includes specific functional groups that contribute to its biological activity. As with many pharmacological agents, the safety profile, efficacy, and pharmacokinetics of Foropafant are subjects of ongoing research to better understand its potential uses in clinical settings.

Formula: C₂₈H₄₀N₄S

InChI: InChI=1/C28H40N4S/c1-19(2)23-14-24(20(3)4)27(25(15-23)21(5)6)26-18-33-28(30-26)32(13-12-31(7)8)17-22-10-9-11-29-16-22/h9-11,14-16,18-21H,12-13,17H2,1-8H3

SMILES: CC(C)c1cc(C(C)C)c(c(c1)C(C)C)c1csc(n1)N(CCN(C)C)Cc1cccnc1

Synonyms:

• Sr 27417
• N,N-dimethyl-N'-(pyridin-3-ylmethyl)-N'-{4-[2,4,6-tri(propan-2-yl)phenyl]-1,3-thiazol-2-yl}ethane-1,2-diamine

1,2-Ethanediamine, N1,N1-dimethyl-N2-(3-pyridinylmethyl)-N2-[4-[2,4,6-tris(1-methylethyl)phenyl]-2-thiazolyl]-

CAS: 136468-36-5

Formula: C₂₈H₄₀N₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 464.7090

Ref: IN-DA0011WH

Foropafant

CAS: 136468-36-5

Foropafant

Purity: ≥98%

Molecular weight: 464.71g/mol

Ref: 54-BUP08679

Foropafant

CAS: 136468-36-5

Foropafant (SR27417) is a highly potent and selective platelet-activating factor (PAF) receptor antagonist (Ki: 57 pM).

Formula: C₂₈H₄₀N₄S

Purity: 99.67%

Color and Shape: Solid

Molecular weight: 464.71

Ref: TM-T15338