CAS 1365267-37-3

2-[[[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]amino]carbonyl]benzoic acid

Description:

The chemical substance known as 2-[[[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]amino]carbonyl]benzoic acid, with the CAS number 1365267-37-3, is characterized by its complex molecular structure, which includes an oxazolidine ring, a benzoic acid moiety, and a morpholine derivative. This compound is likely to exhibit properties typical of both amides and carboxylic acids, including potential solubility in polar solvents and the ability to form hydrogen bonds due to the presence of functional groups such as the carboxylic acid and amine. The oxazolidine ring suggests potential biological activity, possibly as an antibiotic or in other therapeutic applications, as oxazolidinones are known for their role in medicinal chemistry. Additionally, the presence of multiple functional groups indicates that this compound may participate in various chemical reactions, making it a candidate for further research in drug development or synthetic chemistry. Its stereochemistry, particularly the (5S) configuration, may also influence its biological activity and interaction with biological targets.

Formula: C₂₂H₂₁N₃O₇

InChI: InChI=1S/C22H21N3O7/c26-19-13-31-10-9-24(19)14-5-7-15(8-6-14)25-12-16(32-22(25)30)11-23-20(27)17-3-1-2-4-18(17)21(28)29/h1-8,16H,9-13H2,(H,23,27)(H,28,29)/t16-/m0/s1

InChI key: InChIKey=OXEFOWVRNIRGLF-INIZCTEOSA-N

SMILES: O=C1N(C[C@H](CNC(=O)C2=C(C(O)=O)C=CC=C2)O1)C3=CC=C(C=C3)N4C(=O)COCC4

Synonyms:

• (S)-2-(((2-Oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)carbamoyl)benzoic acid
• 2-[[[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]amino]carbonyl]benzoic acid
• Benzoic acid, 2-[[[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]amino]carbonyl]-

Benzoic acid, 2-[[[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]amino]carbonyl]-

CAS: 1365267-37-3

Formula: C₂₂H₂₁N₃O₇

Purity: 97%

Color and Shape: Solid

Molecular weight: 439.4180

Ref: IN-DA009C9M

(S)-2-(((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)carbamoyl)benzoic acid

CAS: 1365267-37-3

(S)-2-(((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)carbamoyl)benzoic acid

Purity: 96%

Molecular weight: 439.42g/mol

Ref: 54-OR89767

(S)-2-(((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)carbamoyl)benzoic acid

CAS: 1365267-37-3

Purity: 97%

Molecular weight: 439.42401123046875

Ref: 10-F789824

Rivaroxaban O-Carboxy Benzamide Impurity

CAS: 1365267-37-3

Formula: C₂₂H₂₁N₃O₇

Molecular weight: 439.43

Ref: 4Z-R-2921

2-[[[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]amino]carbonyl]-benzoic Acid

Controlled Product

CAS: 1365267-37-3

Applications 2-[[[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]amino]carbonyl]-benzoic Acid is an intermediate used in the synthesis of Bis-[Des(5-Chloro-2-carboxythienyl)] Rivaroxaban Phthalamide (B415135), which is an impurity of Rivaroxaban (R538000), a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.
References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),

Formula: C₂₂H₂₁N₃O₇

Color and Shape: Neat

Molecular weight: 439.418

Ref: TR-O870240

Rivaroxaban Impurity 31

CAS: 1365267-37-3

Formula: C₂₂H₂₁N₃O₇

Molecular weight: 439.4

Ref: ST-EA-CP-R17091