CAS 136554-94-4
:Fmoc-D-Trp-OPfp
Description:
Fmoc-D-Trp-OPfp, with the CAS number 136554-94-4, is a chemical compound commonly used in peptide synthesis and research. It is a derivative of tryptophan, specifically the D-enantiomer, and features a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely utilized in solid-phase peptide synthesis to protect the amino group during the coupling process. The compound also contains an OPfp (pentafluorophenyl) ester, which serves as an activated carboxylic acid moiety, facilitating the formation of peptide bonds. Fmoc-D-Trp-OPfp is characterized by its stability under basic conditions and its ability to undergo deprotection under mild acidic conditions, making it suitable for sequential peptide synthesis. Its unique structure allows for the incorporation of D-tryptophan into peptides, which can influence the biological activity and stability of the resulting compounds. Overall, Fmoc-D-Trp-OPfp is a valuable reagent in the field of peptide chemistry, particularly for synthesizing peptides with specific stereochemical configurations.
Formula:C32H21F5N2O4
InChI:InChI=1/C32H21F5N2O4/c33-25-26(34)28(36)30(29(37)27(25)35)43-31(40)24(13-16-14-38-23-12-6-5-7-17(16)23)39-32(41)42-15-22-20-10-3-1-8-18(20)19-9-2-4-11-21(19)22/h1-12,14,22,24,38H,13,15H2,(H,39,41)/t24-/m1/s1
SMILES:c1ccc2c(c1)c1ccccc1C2COC(=N[C@H](Cc1c[nH]c2ccccc12)C(=O)Oc1c(c(c(c(c1F)F)F)F)F)O
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 1 products.
