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CAS 136555-16-3

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FMOC-D-CPG-OH

Description:
FMOC-D-CPG-OH, or 9-fluorenylmethoxycarbonyl-D-cyano-2,3-dihydro-1H-pyrrole-1-carboxylic acid, is a chemical compound commonly used in peptide synthesis as a protecting group for amino acids. Its structure features a fluorenylmethoxycarbonyl (FMOC) group, which is a stable and easily removable protecting group that facilitates the selective functionalization of amino acids during solid-phase peptide synthesis. The compound is typically characterized by its solid-state form, exhibiting stability under standard laboratory conditions. FMOC-D-CPG-OH is soluble in organic solvents such as dimethylformamide (DMF) and dichloromethane, making it suitable for various synthetic applications. The FMOC group can be removed under mild basic conditions, allowing for the subsequent coupling of amino acids without significant side reactions. This compound is particularly valuable in the field of medicinal chemistry and biochemistry for the synthesis of peptides and other complex organic molecules. Its use enhances the efficiency and specificity of peptide synthesis, contributing to advancements in drug development and biochemical research.
Formula:C22H23NO4
Synonyms:
  • Fmoc-D-Cyclopentylglycine
  • Fmoc-D-Cycpentgly-Oh
  • Fmoc-Cyclopentyl-D-Gly-Oh
  • Fmoc-D-Gly(Cyclopentyl)-Oh
  • (R)-2-Cyclopentyl-2-(Fmoc-Amino)-Acetic Acid
  • N-Alpha-(9-Fluorenylmethyloxycarbonyl)-D-Cyclopentylglycine
  • N-Alpha-(9-Fluorenylmethyloxycarbonyl)-D-Beta-Cyclopentylglycine
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