CAS 136565-60-1

L-α-Dilauroyl Phosphatidylcholine-d46

Description:

L-α-Dilauroyl Phosphatidylcholine-d46 is a synthetic phospholipid, specifically a derivative of phosphatidylcholine, which is a major component of biological membranes. This compound features two lauric acid (dodecanoic acid) chains, contributing to its hydrophobic characteristics, while the phosphocholine head group provides a hydrophilic region, making it amphiphilic. The "d46" designation indicates that the molecule is isotopically labeled with deuterium, which is often used in NMR spectroscopy and other analytical techniques to study molecular dynamics and interactions. The presence of deuterium enhances the resolution of spectroscopic data, allowing for detailed investigations of lipid behavior in various environments. L-α-Dilauroyl Phosphatidylcholine-d46 is commonly utilized in biophysical studies, drug delivery systems, and membrane model systems due to its ability to form lipid bilayers and vesicles. Its unique properties make it valuable for research in cell biology, pharmacology, and biochemistry, particularly in understanding membrane dynamics and interactions with proteins and other biomolecules.

Formula: C₃₂H₆₄NO₈P

Synonyms:

• L-α-Dilauroyl Phosphatidylcholine-d46

L-α-Dilauroyl Phosphatidylcholine-d46

Controlled Product

CAS: 136565-60-1

Applications Labelled L-α-Dilauroyl Phosphatidylcholine forms robust and versatile membrane bilayers to study the selective and ATP-driven transport ions across membranes into nanoporous carriers using gramicidin A and ATP synthase. It is used in the preparation of other phosphatidylcholines.
References Tomoi, M. et al.: Synth. Comm., 19, 905 (1989); Ichihara, K. et al.: Chem. Phys. Lipids., 137, 94 (2005); Olliynyk, V., et al.: Phys. Chem. Chem. Phys., 15, 2733 (2013); Podloucka, P., et al.: J. Phy. Chem. B., 117, 5043 (2013);

Formula: C₃₂H₁₈D₄₆NO₈P

Color and Shape: Neat

Molecular weight: 668.11

Ref: TR-D446657