CAS 136668-42-3

Quiflapon

Description:

Quiflapon, with the CAS number 136668-42-3, is a chemical compound that belongs to the class of quinoline derivatives. It is primarily recognized for its potential applications in medicinal chemistry, particularly as an antimalarial agent. The compound exhibits a complex molecular structure that contributes to its biological activity. Quiflapon is characterized by its ability to interact with various biological targets, which may include enzymes and receptors involved in disease processes. Its pharmacological profile suggests that it may possess both antiprotozoal and antibacterial properties, making it a subject of interest in drug development. Additionally, the compound's solubility, stability, and bioavailability are critical factors that influence its efficacy and therapeutic potential. As with many chemical substances, safety and toxicity assessments are essential for determining its suitability for clinical use. Overall, Quiflapon represents a promising candidate in the search for new therapeutic agents, particularly in the context of infectious diseases.

Formula: C₃₄H₃₅ClN₂O₃S

InChI: InChI=1/C34H35ClN2O3S/c1-33(2,3)41-31-27-18-26(40-21-25-15-12-23-8-6-7-9-28(23)36-25)16-17-29(27)37(20-22-10-13-24(35)14-11-22)30(31)19-34(4,5)32(38)39/h6-18H,19-21H2,1-5H3,(H,38,39)

SMILES: CC(C)(C)Sc1c2cc(ccc2n(Cc2ccc(cc2)Cl)c1CC(C)(C)C(=O)O)OCc1ccc2ccccc2n1

Synonyms:

• Mk 0591
• 3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropanoic acid

Quiflapon

CAS: 136668-42-3

Quiflapon (MK-591) is a potent, selective FLAP inhibitor (IC50: 1.6 nM) and oral LT biosynthesis blocker in humans and rats (IC50: 3.1/6.1 nM).

Formula: C₃₄H₃₅ClN₂O₃S

Purity: 98.88%

Color and Shape: Solid

Molecular weight: 587.17

Ref: TM-T16087

1-[(4-Chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-α,α-dimethyl-5-(2-quinolinylmethoxy)-1H-indole-2-propanoic acid

CAS: 136668-42-3

Formula: C₃₄H₃₅ClN₂O₃S

Purity: 98%

Molecular weight: 587.1713

Ref: IN-DA001278

Quiflapon

CAS: 136668-42-3

Quiflapon

Purity: ≥95%

Molecular weight: 587.17g/mol

Ref: 54-BUP11508

Quiflapon

CAS: 136668-42-3

Quiflapon is a drug that belongs to the class of non-steroidal anti-inflammatory drugs. It is used for the treatment of inflammation and pain associated with conditions such as bronchial asthma, resistant breast cancer, inflammatory bowel disease, and autoimmune diseases. Quiflapon has been shown to increase the rate at which fluid leaves the body through urination (glomerular filtration rate) by blocking the production of prostaglandins that are responsible for increasing renal blood flow. It also inhibits protease activity, thereby reducing inflammation in the bowel. Quiflapon may be effective in treating bowel diseases such as ulcerative colitis or Crohn's disease by inhibiting toll-like receptor 4 (TLR4) signalling pathways in immune cells.

Formula: C₃₄H₃₅ClN₂O₃S

Purity: Min. 95%

Molecular weight: 587.17 g/mol

Ref: 3D-LFA66842