CAS 136725-53-6

S-(+)-3-Fluoropyrrolidine hydrochloride

Description:

S-(+)-3-Fluoropyrrolidine hydrochloride is a chiral organic compound characterized by its pyrrolidine ring structure, which is a five-membered saturated nitrogen-containing heterocycle. The presence of a fluorine atom at the 3-position of the pyrrolidine ring contributes to its unique chemical properties, including potential effects on biological activity and reactivity. As a hydrochloride salt, it is typically encountered in a crystalline form, which enhances its solubility in polar solvents, making it suitable for various applications in medicinal chemistry and drug development. The compound is known for its potential use in the synthesis of pharmaceuticals, particularly in the development of central nervous system agents. Its chirality, indicated by the S-(+) designation, suggests that it may exhibit specific interactions with biological targets, which is crucial in the context of drug efficacy and safety. Overall, S-(+)-3-Fluoropyrrolidine hydrochloride is an important compound in the field of organic synthesis and pharmacology, with ongoing research into its properties and applications.

Formula: C₄H₉NClF

Synonyms:

• (R)-(-)-3-Fluoropyrrolidine hydrochloride
• (3S)-(+)-3-Fluoropyrrolidine hydrochloride
• (S)-3-Fluoropyrrolidine HCl

(S)-(+)-3-Fluoropyrrolidine hydrochloride, 97%

CAS: 136725-53-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₄H₉ClFN

Purity: 97%

Color and Shape: Crystals or powder or crystalline powder, Pale pink or pale cream

Molecular weight: 125.57

Ref: 02-H27536

(S)-(+)-3-Fluoropyrrolidine, HCl

CAS: 136725-53-6

Formula: C₄H₉ClFN

Purity: 97%

Color and Shape: Solid

Molecular weight: 125.5724

Ref: IN-DA00129V

(3S)-(+)-3-Fluoropyrrolidine hydrochloride

CAS: 136725-53-6

(3S)-(+)-3-Fluoropyrrolidine hydrochloride

Formula: C₄H₈FN·ClH

Purity: ≥95%

Color and Shape: white to off-white solid

Molecular weight: 125.57g/mol

Ref: 54-PC6738

(S)-3-Fluoropyrrolidine Hydrochloride

CAS: 136725-53-6

Formula: C₄H₈FN·HCl

Purity: >98.0%(T)

Color and Shape: White to Brown powder to crystal

Molecular weight: 125.57

Ref: 3B-F1344

(S)-(+)-3-Fluoropyrrolidine HCl

CAS: 136725-53-6

(S)-(+)-3-Fluoropyrrolidine HCl is a dipeptidyl peptidase inhibitor that has been shown to inhibit the activity of dipeptidyl peptidase IV (DPP-IV). It is orally active and has a pharmacokinetic profile that includes a rapid absorption, good bioavailability, and short elimination half-life. The drug also has high selectivity for DPP-IV inhibition over other enzymes, such as aminopeptidase P. (S)-(+)-3-Fluoropyrrolidine HCl analogues have been developed, including those with substitutions on the central carbon atom or on the nitro group. These analogues are more potent than their parent compound and show increased selectivity for DPP-IV inhibition.

Formula: C₄H₉ClFN

Purity: Min. 95%

Molecular weight: 125.57 g/mol

Ref: 3D-FF50598

(S)-3-Fluoropyrrolidine hydrochloride

CAS: 136725-53-6

Formula: C₄H₉ClFN

Purity: 97%

Color and Shape: Solid

Molecular weight: 125.57

Ref: 10-F013157